CEP97

CEP97
Identifiers
Aliases	CEP97, 2810403B08Rik, LRRIQ2, centrosomal protein 97
External IDs	OMIM: 615864 MGI: 1921451 HomoloGene: 11579 GeneCards: CEP97
Gene location (Human) Chr. Chromosome 3 (human) Band 3q12.3 Start 101,724,593 bp End 101,770,562 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band 16|16 C1.1 Start 55,720,251 bp End 55,755,218 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum endothelial cell inferior ganglion of vagus nerve oocyte internal globus pallidus secondary oocyte superior vestibular nucleus subthalamic nucleus ganglionic eminence ventral tegmental area Top expressed in hand otolith organ utricle thymus cumulus cell blood pineal gland ciliary body spermatocyte foot More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding calmodulin binding Cellular component centrosome cytoskeleton microtubule organizing center cytoplasm cytosol protein-containing complex Biological process cell projection organization negative regulation of cilium assembly regulation of mitotic spindle assembly ciliary basal body-plasma membrane docking Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79598 74201 Ensembl ENSG00000182504 ENSMUSG00000022604 UniProt Q8IW35 Q9CZ62 RefSeq (mRNA) NM_001303401 NM_024548 NM_001159364 NM_001159365 NM_001159366 NM_028815 RefSeq (protein) NP_001290330 NP_078824 NP_001152836 NP_001152837 NP_001152838 NP_083091 Location (UCSC) Chr 3: 101.72 – 101.77 Mb Chr 16: 55.72 – 55.76 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene.

Cep97 along with CP110 inhibit generation of cilia.

External links

• Human CEP97 genome location and CEP97 gene details page in the UCSC Genome Browser.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Svendsen JM, Smogorzewska A, Sowa ME, et al. (2009). "Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair". Cell. 138 (1): 63–77. doi:10.1016/j.cell.2009.06.030. PMC 2720686. PMID 19596235.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Bettencourt-Dias M, Carvalho-Santos Z (2008). "Double life of centrioles: CP110 in the spotlight". Trends Cell Biol. 18 (1): 8–11. doi:10.1016/j.tcb.2007.11.002. PMID 18068367.
• Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell. Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.
• Tsang WY, Spektor A, Vijayakumar S, et al. (2009). "Cep76, a centrosomal protein that specifically restrains centriole reduplication". Dev. Cell. 16 (5): 649–660. doi:10.1016/j.devcel.2009.03.004. PMC 4062978. PMID 19460342.