CEP72

CEP72
Identifiers
Aliases	CEP72, centrosomal protein 72
External IDs	OMIM: 616475 MGI: 1921720 HomoloGene: 10027 GeneCards: CEP72
Gene location (Human) Chr. Chromosome 5 (human) Band 5p15.33 Start 612,340 bp End 667,168 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 C1 Start 74,184,619 bp End 74,210,418 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere ganglionic eminence sural nerve right uterine tube skin of abdomen palpebral conjunctiva caudate nucleus Brodmann area 9 nucleus accumbens prefrontal cortex Top expressed in spermatocyte spermatid seminiferous tubule morula thymus neural tube ganglionic eminence yolk sac abdominal wall cerebellar cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding Cellular component cytoplasm microtubule organizing center cytosol centrosome centriolar satellite cytoskeleton Biological process gamma-tubulin complex localization centriole replication spindle organization G2/M transition of mitotic cell cycle regulation of protein localization to centrosome ciliary basal body-plasma membrane docking regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55722 74470 Ensembl ENSG00000280688 ENSG00000112877 ENSMUSG00000021572 UniProt Q9P209 Q9D3R3 RefSeq (mRNA) NM_018140 NM_028959 RefSeq (protein) NP_060610 NP_083235 Location (UCSC) Chr 5: 0.61 – 0.67 Mb Chr 13: 74.18 – 74.21 Mb PubMed search
Wikidata
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Centrosomal protein of 72 kDa is a protein that in humans is encoded by the CEP72 gene.

The product of this gene is a member of the Leucine-rich repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Andersen JS, Wilkinson CJ, Mayor T, et al. (2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature. 426 (6966): 570–4. Bibcode:2003Natur.426..570A. doi:10.1038/nature02166. PMID 14654843. S2CID 4427303.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

External links

• Human CEP72 genome location and CEP72 gene details page in the UCSC Genome Browser.