CDP-glycerol diphosphatase

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CDP-glycerol diphosphatase
Identifiers
EC no.3.6.1.16
CAS no.37289-28-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a CDP-glycerol diphosphatase (EC 3.6.1.16) is an enzyme that catalyzes the chemical reaction

CDP-glycerol + H2O CMP + sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are CDP-glycerol and H2O, whereas its two products are CMP and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-glycerol phosphoglycerohydrolase. Other names in common use include CDP-glycerol pyrophosphatase, and cytidine diphosphoglycerol pyrophosphatase. This enzyme participates in glycerophospholipid metabolism.

References

  • Glaser L (March 1965). "The synthesis of teichoic acid IV. On the regulation of cytidine 5′-diphosphateglycerol concentration". Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides. 101: 6–15. doi:10.1016/0926-6534(65)90025-4. PMID 14329291.