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Timing of symptoms
Symptoms in children
A person may be infectious to others both before, and during, the time they are showing symptoms.
Antiviral drugs such as the neuraminidase inhibitor oseltamivir, have been used to treat influenza, but the benefit to otherwise healthy patients does not appear to be greater than the risks,  and no benefit has been found in those with other health problems.
Influenza spreads around the world in yearly outbreaks, resulting in three to five million cases of severe illness, and 250 to 500 thousand deaths. About 20% of unvaccinated children, and 10% of unvaccinated adults are infected each year.
Highest risk of death
In the 20th century, three influenza pandemics occurred.
The Spanish influenza in 1918 that resulted in 50 million deaths,
The Asian influenza in 1957 that killed two million,
Hong Kong influenza
Influenza may also affect other animals, including pigs, horses, and birds.
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