Template:Parenteral potencies and durations of progestogens

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Parenteral potencies and durations of progestogens
Progestogen Form Major brand names Class TFD
(14 days)		 POIC-D
(2–3 months)		 CIC-D
(month)		 Duration
Algestone acetophenide Oil solution Perlutal, Topasel, Yectames Pregnane ? – 75–150 mg 100 mg ≈ 14–32 days
Cyproterone acetate Oil solution Androcur Depot Pregnane ? – – 300 mg ≈ 20 days
Dydrogesteronea Aqueous suspension – Retropregnane ? – – 100 mg ≈ 16–38 days
Gestonorone caproate Oil solution Depostat, Primostat Norpregnane 25–50 mg – – 25–50 mg ≈ 8–13 days
Hydroxyprogesterone acetatea Aqueous suspension – Pregnane 350 mg – – 150–350 mg ≈ 9–16 days
Hydroxyprogesterone caproate Oil solution Delalutin, Proluton, Makena Pregnane 250–500 mgb – 250–500 mg 65–500 mg ≈ 5–21 days
Levonorgestrel butanoatea Aqueous suspension – Gonane ? – – 5–50 mg ≈ 3–6 months
Lynestrenol phenylpropionatea Oil solution – Estrane ? – – 50–100 mg ≈ 14–30 days
Medroxyprogesterone acetate Aqueous suspension Depo-Provera Pregnane 50–100 mg 150 mg 25 mg 50–150 mg ≈ 14–50+ days
Megestrol acetate Aqueous suspension Mego-E Pregnane ? – 25 mg 25 mg ≈ >14 daysc
Norethisterone enanthate Oil solution Noristerat, Mesigyna Estrane 100–200 mg 200 mg 50 mg 50–200 mg ≈ 11–52 days
Oxogestone phenylpropionatea Oil solution – Norpregnane ? – – 100 mg ≈ 19–20 days
Progesterone Oil solution Progestaject, Gestone, Strone Pregnane 200 mgb – – 25–350 mg ≈ 2–6 days
Aqueous suspension Agolutin Depot Pregnane 50–200 mg – – 50–300 mg ≈ 7–14 days
Note: All by intramuscular or subcutaneous injection. All are synthetic except for P4, which is bioidentical. P4 production during the luteal phase is ~25 (15–50) mg/day. The OID of OHPC is 250 to 500 mg/month. Footnotes: a = Never marketed by this route. b = In divided doses (2 × 125 or 250 mg for OHPC, 10 × 20 mg for P4). c = Half-life is ~14 days. Sources: Main: [1][2][3][4][5][6][7][8][9] Additional: [10][11][12][13][14][15][16][17][18][19][20]
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