Template:Did you know nominations/Selinexor

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The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: promoted by Yoninah (talk) 00:53, 14 August 2019 (UTC)

Selinexor

  • ... that selinexor is the first anti-cancer drug to work by inhibiting exportin 1? Source: "Selinexor (KPT-330) is the first-in-human SINE compound" [1]
    • ALT1:... that selinexor is the first drug for multiple myeloma which has returned or persisted despite five previous treatments? "Selinexor is the first FDA-approved medication for this indication." [2]
    • ALT2:... that by approving selinexor, the FDA overruled its own panel of independent experts, which had voted 8–5 against the anti-cancer drug? [3]
  • Reviewed: Paracoccidioides lutzii
  • Comment: I'm aware this may be of limited interest to the general reader. However, this is a pretty interesting drug for a common cancer, with a unique mechanism of action and a unique indication, which has just been approved (quite controversially) by the U.S. FDA. The article is sourced entirely from free, open-access secondary and tertiary WP:MEDRS and I have tried to make it as legible as possible considering the technical subject matter. I've only ever proposed two DYKs before and haven't done so in years, so apologies if I got the process wrong.

Created by Fvasconcellos (talk). Self-nominated at 13:21, 7 July 2019 (UTC).

  • This article is new enough and long enough. The hook facts of all three hooks are cited inline, the article is neutral and I detected no copyright or plagiarism issues. A QPQ has been done. Cwmhiraeth (talk) 06:37, 12 July 2019 (UTC)