Talk:SymE-SymR toxin-antitoxin system

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Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 9 March 2020 and 29 May 2020. Further details are available on the course page. Student editor(s): Sieradzkig. Peer reviewers: Sabrina Mierswa, Imasciencer.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 10:35, 17 January 2022 (UTC)[reply]

Highlights From Three Articles/References

The following are pieces of information found from three different articles that showcase more information that could be added to improve the article:

1) SymE/SymR may be involved in recycling damaged RNA as part of the stress response for bacteria. Additionally, symE specifically has LexA binding sites that are induced by the stress response.[1]

2) SymE is a toxin superfamily. Traditionally, antitoxin is sRNA and toxin/antitoxin genes exist in opposite strands of type I systems.[2]

3) SymE is not hydrophobic and is apparently in the cytoplasm. Its homology is similar to type II toxins, and it is considered an RNase.[3]

Sieradzkig (talk) 03:05, 21 April 2020 (UTC)[reply]

References

  1. ^ Peter Müller, Natalie Jahn, Christiane Ring, Caroline Maiwald, Robert Neubert, Christin Meißner & Sabine Brantl (2016) A multistress responsive type I toxin-antitoxin system: bsrE/SR5 from the B. subtilis chromosome, RNA Biology, 13:5, 511-523, DOI: 10.1080/15476286.2016.1156288
  2. ^ Lillian G. Acuña, M. José Barros, Paula Nuñez, Diego Peñaloza, Fernanda Montt, Diego Pedraza, Katherine Crossley, Fernando Gil, Juan A. Fuentes, Iván L. Calderón. (2020).The cis-encoded antisense RNA IsrA from Salmonella Typhimurium represses the expression of STM0294.1n (iasE), an SOS-induced gene coding for an endoribonuclease activity,Biochemical and Biophysical Research Communications, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2020.03.131. (http://www.sciencedirect.com/science/article/pii/S0006291X20306227)
  3. ^ Maeda, T., Tanaka, Y. and Inui, M. (2018), Glutamine‐rich toxic proteins GrtA, GrtB and GrtC together with the antisense RNA AsgR constitute a toxin–antitoxin‐like system in Corynebacterium glutamicum. Molecular Microbiology, 108: 578-594. doi:10.1111/mmi.13951
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