Wikipedia talk:WikiProject Molecular Biology

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Welcome to the WikiProject Molecular Biology talk page. Please post any comments, suggestions or questions. Also feel free to introduce yourself if you plan on becoming an active editor!

WikiProject Molecular Biology Archives: 1, 2, 3

Taskforce archives:

MCB: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Genetics: 1, 2, 3, 4
Computational Biology: 1, 2
Gene Wiki: 1, 2, 3, 4

Biophysics (inactive): 1, 2
Metabolic Pathways (inactive): 1
Cell Signaling (inactive): 1
RNA (inactive): 1

Requested move at Talk:NC ratio#Requested move 19 January 2024

There is a requested move discussion at Talk:NC ratio#Requested move 19 January 2024 that may be of interest to members of this WikiProject. – robertsky (talk) 07:15, 31 January 2024 (UTC)[reply]

Agouti

I was trying to make sense of Agouti (coloration) when I realized that the following articles exist:

My confusion here comes from the overlap and vague scope between all of these articles. Agouti-related peptide also exists but I see no problem with it, it just gets lumped in with the rest due to the name. Agouti-signaling protein and Agouti coloration genetics seem to have a lot of overlap, only that the latter is a list of all the genes related to agouti coloration and the former is a more useful, if somewhat technical, overview of the gene. What I'd like to know is if a merge is possible or if there's some better approach that I don't see because I'm not familiar enough with molecular biology to say. Also, would like to figure out the scope of Agouti (coloration) because it's not in a good spot right now, but there isn't much room for it to grow without getting into genetics. Reconrabbit 00:25, 1 February 2024 (UTC)[reply]

I'd probably have one article for the gene and another for the colouration. We don't need 2 articles for the colouration. Jo-Jo Eumerus (talk) 12:51, 1 February 2024 (UTC)[reply]
A bit ago the article on coloration was merged with coloration genetics, presumably very poorly as it was un-merged later. I could try to do it again after putting it up for comment? Reconrabbit 13:21, 1 February 2024 (UTC)[reply]

Request to create a new article

Good day Computational Biology taskforce, I am writing to request the creation of a new article. I need your help, because I want to participate in (Wikipedia:WikiProject Molecular Biology/Computational Biology/13th ISCB Student Wikipedia competition announcement) https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Molecular_Biology/Computational_Biology/13th_ISCB_Student_Wikipedia_competition_announcement . Is possible ???? The title of new article is "El espacio químico de la vida" because I want to participe in OTHER LANGUAGES. Thank you very much for time and help me.https://es.wikipedia.org/wiki/El_espacio_qu%C3%ADmico_de_la_vida

Excellent day, Haikluum (talk) 23:09, 2 February 2024 (UTC)[reply]

Pinging @Tkarakulak, @NellySelem.
Haikluum, I don't speak Spanish but it seems the page https://es.wikipedia.org/wiki/El_espacio_qu%C3%ADmico_de_la_vida was deleted due to a copyright violation - not sure if this was a draft you started? Please note the competition rules on plagiarism and copyright; these are Wikipedia guidelines as well. Amkilpatrick (talk) 10:35, 3 February 2024 (UTC)[reply]
Hello I'm not sure about the copy-right violation, grammarly says its original text. Perhaps, you need to ask the user Saloca about why he considers that this is infringes copyright. NellySelem (talk) 05:31, 5 February 2024 (UTC)[reply]

Irrelevant section in certain article - what's your opinion?

Im reading a section "Research areas/P53 mutations in Apoptosis" in apoptosome over and over, but it seems to me, this section is completely unrelated to the subject of the article, apoptosome itself. I don't want to delete it right of the bat though. It looks like, with two preceding sections, like an informal introduction to the fourth one, hence this little thread in Wikiproject. InternetowyGołąb (talk) 02:13, 15 February 2024 (UTC)[reply]

Oy, yeah, that section is about p53 or apoptosis, not the apoptosome. Jo-Jo Eumerus (talk) 07:34, 15 February 2024 (UTC)[reply]

APETx1 article - Infobox error

Greetings, For article APETx1, at top it shows error line in red, Unknown parameter SequenceUnknown parameter Amino Acid Sequence. Asking for help here as I know almost nothing of the topic. Regards, JoeNMLC (talk) 20:01, 15 February 2024 (UTC)[reply]

The infobox parameters have been corrected, thank you. ― Synpath 20:40, 18 February 2024 (UTC)[reply]

Delete "Gene expression" article

I propose that we delete the article on Gene expression and replace it with redirects to relevant material found elsewhere such as Transcription, Translation, and Regulation of gene expression.

It's a bad idea to have multiple articles covering the same topic, especially when they conflict. Also, the Gene expression article is far too big and full of extraneous technical information that's way beyond the level we should be aiming at.Genome42 (talk) 21:47, 17 February 2024 (UTC)[reply]

Gene expression is a fundamental topic in molecular biology; we need an article on the topic. I agree there are many facets to this broad and deep topic. The current organization, which introduces the topic, provides summaries and links to other more specialized topics, seems a good structure to reflect these facets. If there are sections that are too technical, those would be good candidates for a rewrite, but not a deletion. Let's not delete the forest to get at the trees. --{{u|Mark viking}} {Talk} 00:23, 18 February 2024 (UTC)[reply]
Gene expression is represented as a whole process in biology textbooks. With the use of "Main article" templates, more interested reader shoudn't face any problems with finding more information. InternetowyGołąb (talk) 03:06, 18 February 2024 (UTC)[reply]
As a textbook writer and teacher I'm quite familiar with how the topic of gene expression is covered in molecular biology. We usually cover transcription and translation in some detail then we cover the basics of regulation of gene expression. All three of those topics are presented in separate articles on Wikipedia.
There's nothing in the article on gene expression that's not found elsewhere. The problem isn't just redundancy. It's that various editors insert their own biases and (possibly) misinformation into the various articles so that the more articles we have the greater the chance that they will conflict. There aren't very many of us working on these articles so let's concentrate on getting a few articles correct. Genome42 (talk) 21:09, 18 February 2024 (UTC)[reply]
Check out the Gene expression article to see examples extraneous information. There are sections on "Folding," "Translocation," and "Protein transport." Are those really relevant topics in an article on gene expression?
The section on "Regulation of gene expression" only talks about the complex mechanisms in eukaryotes. There's nothing about the lac operon or the other fundamental examples in bacteria. There's nothing about how a transcription factor finds the right gene. Some of the material that's in that section is either incomplete or misleading. There's a section on methylation that doesn't even mention chromatin and doesn't explain why some CpGs are demethylated.
There's an entire section on "Transcriptional regulation in learning and memory" and another on "Transcriptional regulation in cancer." Really? There's a lengthy section on "Measurement" that's far too detailed, boring, and doesn't cite any sources. Does anybody really want to waste time cleaning up this article?Genome42 (talk) 21:34, 18 February 2024 (UTC)[reply]
Gene expression is a solid example of a WP:BROAD concept. I don't think you could redirect the term to a single article and have that be satisfactory. I don't think it would be possible to build it into a disambiguation either. The current organization of a set of summarized subtopics linking to main articles is likely the best way of handling the term. Though I do agree that the article has bloat. ― Synpath 21:36, 18 February 2024 (UTC)[reply]

"Random sequencing"

On our Mycoplasma genitalium article, it says:

They performed an initial study of the genome using random sequencing in 1993

where "random sequencing" links to Random sequence (the mathematical concept). What should it link to instead? Marnanel (talk) 13:39, 2 March 2024 (UTC)[reply]

It should link to DNA sequencing where you can find descriptions of early sequencing techniques. Randomness is a core part of several techniques, but there's no dedicated section describing its use in that article. I don't think that the word 'random' should be part of the wikilink. ― Synpath 16:17, 2 March 2024 (UTC)[reply]
Done— thank you. I note that "random" was in the title and abstract of the linked paper, which is presumably where the previous editor found it. Marnanel (talk) 21:04, 2 March 2024 (UTC)[reply]

Zoonotic origins of COVID-19

Zoonotic origins of COVID-19 has been nominated at Articles for Deletion. Interested editors may participate at Wikipedia:Articles for deletion/Zoonotic origins of COVID-19. TarnishedPathtalk 09:47, 9 March 2024 (UTC)[reply]

Unused PDB Gallery templates

Hey everyone, the following PDB Gallery templates are not used anywhere. If you know where they should be used, please use them in the relevant articles. If they aren't needed please let me know.

Thanks! Gonnym (talk) 15:39, 13 March 2024 (UTC)[reply]

Appropriate template for gene/protein synonyms

Recently I made some protein or gene (article about protein with title being gene descriptor) synonymous names redirects, and I wonder what would be the appropriate "R from..." tracking category template. InternetowyGołąb (talk) 13:15, 23 March 2024 (UTC)[reply]

@InternetowyGołąb We have alternatives like {{R from acronym}} and {{R from initialism}} as well as the tracking Category {{R from alternative name}} I see you have used for NAXE. The template pages give guidance on which to use: in some cases more than one is appropriate. Mike Turnbull (talk) 12:08, 8 April 2024 (UTC)[reply]

Atavism: Real or psuedoscience?

Folks - quick question because I'm not a biologist or scientist by any stretch of the imagination. Is Atavism real or is this a psuedoscience article that has evaded detection? There appears to be a lot of synthesis or original research.--57.140.108.63 (talk) 03:12, 8 April 2024 (UTC)[reply]

Atavism seems to be a legitimate concept but it wouldn't surprise me if it's sometimes used by fringe claims. Jo-Jo Eumerus (talk) 07:07, 8 April 2024 (UTC)[reply]
Since it is tagged with {{Original research}}, it does look like the article needs to be bolstered with citations. Peaceray (talk) 07:40, 8 April 2024 (UTC)[reply]
Possibly a bit of both. A Google Scholar search for "atavism" in article titles gives over 100 hits since the year 2010, of which this article is a reasonable review. Mike Turnbull (talk) 11:50, 8 April 2024 (UTC)[reply]

Requested move at Talk:3α-Hydroxysteroid dehydrogenase#Requested_move_9_April_2024

There is a requested move discussion at Talk:3α-Hydroxysteroid dehydrogenase#Requested_move_9_April_2024 that may be of interest to members of this WikiProject. Natg 19 (talk) 23:23, 18 April 2024 (UTC)[reply]

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