Talk:Benzo(a)pyrene

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Add BaP biochem references

Note to contributors/self: add BaP biochemistry references. Lots of scientific reviews have been written, the introductions are usually quite useful for coherent background information. Jed 16:52, 3 January 2006 (UTC)[reply]

Tidy

I think that the interaction paragraph needs tidying. It is not accessible to most people and is hard to read even for experts. What is needed is a more qualitative account, where it is said what is epoxidized. Listing all the chemical names is counterproductive. They can be provided for reference, but should not be in the bulk of the text. I am going to edit it heavily very soon unless original or other interested authors do it. --Vuo 09:53, 15 December 2006 (UTC)[reply]

Did some work on the interaction paragraph and the introduction. Should be clearer. I'll leave the clarification note up until someone else comments on this, preferably someone not as intimate with the gory details of the mechanisms as I am. Jed 17:32, 29 December 2006 (UTC)[reply]
Well, it's still Greek to me, a poor layperson. Annodeus 18:30, 24 January 2007 (UTC)[reply]
What's the most confusing part? It's actually quite important for BaP toxicity that it's not the BaP itself that's toxic, but the metabolite. Given that this is one of the few environmental chemicals that we actually know a lot about the actual molecular specifics of carcinogenisis for, I think it's worth including some of the information. Could be summarized and the detail put into a separate paragraph. Jed 23:33, 2 February 2007 (UTC)[reply]

Ultimate Carcinogen?

This article calls benzo[a]pyrene diol the ultimate carcinogen - is that a fair classification? 66.24.24.5 (talk) 19:59, 24 November 2007 (UTC)[reply]

The wording may not be clear — the point is that benzopyrene is not carcinogenic, only its metabolic product is. Similarly you would say that methanol is not the poison in a methanol poisoning, its metabolic product formic acid is the ultimate poison. The "ultimate" carcinogen in absolute terms (compared to all other substances) is usually taken to be TCDD, or 2,4,7,8-tetrachlorodibenzo-p-dioxin. --Vuo (talk) 21:50, 24 November 2007 (UTC)[reply]
Now, that's a little silly. Dioxin's carcinogenicity in humans has not even been conclusively proved. If it were the "ultimate" carcinogen, we would certainly know it in the aftermath of the Seveso disaster. --Trovatore (talk) 20:29, 5 December 2008 (UTC)[reply]

Rating

Start Class - Although there is information, much of it has "citation needed" statements. Geoking66 03:31, 11 April 2007 (UTC)[reply]

name

I remember coming across this name in my dad's old o-chem books, though I think it used round brackets around the a instead of square ones, and thinking it was odd, but I never found out the reason for the a. Is there, for example, a benzo[b]pyrene? --Trovatore (talk) 20:32, 5 December 2008 (UTC)[reply]

I have a similar question. At first when I read it, I thought it was a mistake. Where does this nomenclature come from? It seems unusual in organic chemistry. 84.112.136.52 (talk) 03:58, 25 April 2014 (UTC)[reply]

Solubility in water

I doubt the solubility in water. This data in EPI WATERNT v.01 is 1.62E-3 mg/L. — Preceding unsigned comment added by 159.226.103.238 (talk) 03:28, 13 April 2010 (UTC)[reply]

Spelling

benzo[a]pyren-7,8-dihydrodiol-9,10-epoxide or benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (different text at the picture and in the text under the picture) — Preceding unsigned comment added by 134.110.24.94 (talk) 17:03, 9 March 2016 (UTC)[reply]

External links modified

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Something Interesting

That looks like a piece of graphite to me. I wonder if this should be merged with the page on graphite. 32ieww (talk) 22:53, 28 September 2016 (UTC)[reply]

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About the systematic name

According to naming of bridge ring compound, this compound can be named pentacyclo[10.6.2.02,7.09,19.016,20]icosa-1,3,5,7,9,11,13,15,17,19-decaene. —339847214sd (talk) 03:24, 5 April 2019 (UTC)[reply]

@339847214sd: - Thank you for your comments - you may be correct about this - however - supporting your edit with a WP:Reliable Source citation (per WP:CITE) may make your edit more acceptable in the article - otherwise - your edit may be considered WP:Original Research, and less acceptable in the article - hope this helps in some way - in any case - Thanks again for your comments - and - Enjoy! :) Drbogdan (talk) 13:21, 5 April 2019 (UTC)[reply]
@Drbogdan: Not original. Please see Bridged compounds#Nomenclature. 339847214sd (talk) 09:32, 9 April 2019 (UTC)[reply]
Thank you for your comments - and link - would still prefer seeing a WP:RS citation for this specific instance - Comments Welcome from other editors - in any case - Enjoy! :) Drbogdan (talk) 15:51, 9 April 2019 (UTC)[reply]
@Drbogdan: This name is derived from "nomenclature of bridged compounds" in IUPAC Nomenclature of Organic Chemistry, like tricyclo[3.3.1.13,7]decane(adamantane). 339847214sd (talk) 16:10, 11 April 2019 (UTC)[reply]

Wiki Education assignment: Toxicology

This article was the subject of a Wiki Education Foundation-supported course assignment, between 10 August 2022 and 8 December 2022. Further details are available on the course page. Student editor(s): Theheathbar01 (article contribs).

— Assignment last updated by Theheathbar01 (talk) 20:05, 17 September 2022 (UTC)[reply]

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