Talk:AU-rich element
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Adenylate/uridylate-rich elements (AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription factors and cytokines. They represent the most common determinant of RNA stability in mammalian cells. Moreover, ARE-directed mRNA degradation is influenced by many exogenous factors, including phorbol esters, calcium ionophores, cytokines and transcription inhibitors. These observations suggest that AREs play a critical role in the regulation of gene expression during cell growth and differentiation, and in the immune response.
The proposed mechanism for which ARE elements function & control sequencing [gif image]
What? Where/how does this fit into the article? What does "control sequencing" mean? 148.177.1.211 (talk) 13:11, 5 November 2015 (UTC)
External links modified
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- Added archive https://web.archive.org/web/20080207173029/http://transterm.otago.ac.nz:80/RNAMotif.html to http://transterm.otago.ac.nz/RNAMotif.html
- Added archive https://web.archive.org/web/20080307031756/http://brp.kfshrc.edu.sa:80/ARED/ to http://brp.kfshrc.edu.sa/ARED/
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{{dead link}}tag to http://rna.tbi.univie.ac.at/cgi-bin/AREsite.cgi
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