RN-9893
Jump to navigation
Jump to search
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
Chemical and physical data | |
Formula | C21H23F3N4O5S |
Molar mass | 500.49 g·mol−1 |
3D model (JSmol) | |
| |
|
RN-9893 is a drug which acts as a potent and selective blocker of the TRPV4 ion channel. It has been used to investigate the role of TRPV4 channels in the function of heart valves.[1][2]
See also
References
- ^ Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, et al. (September 2015). "Identification of orally-bioavailable antagonists of the TRPV4 ion-channel". Bioorganic & Medicinal Chemistry Letters. 25 (18): 4011–5. doi:10.1016/j.bmcl.2015.06.098. PMID 26235950.
- ^ Al-Shammari H, Latif N, Sarathchandra P, McCormack A, Rog-Zielinska EA, Raja S, et al. (2020). "Expression and function of mechanosensitive ion channels in human valve interstitial cells". PLOS ONE. 15 (10): e0240532. Bibcode:2020PLoSO..1540532A. doi:10.1371/journal.pone.0240532. PMC 7561104. PMID 33057457.
Categories:
- Articles with short description
- Short description matches Wikidata
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without UNII source
- Drugs missing an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Piperazines
- Nitro compounds
- Sulfonamides
- Amides
- Isopropyl compounds
- Trifluoromethyl compounds
- All stub articles
- Pharmacology stubs