Protein-coding gene in the species Homo sapiens
Lysine-specific demethylase 4B is an enzyme that in humans is encoded by the KDM4B gene .[5] [6] [7] alpha-ketoglutarate-dependent hydroxylase superfamily.
References
^ a b c GRCh38: Ensembl release 89: ENSG00000127663 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024201 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (6): 355–64. doi :10.1093/dnares/5.6.355 PMID 10048485 . ^ Katoh M, Katoh M (May 2004). "Identification and characterization of JMJD2 family genes in silico". Int J Oncol . 24 (6): 1623–8. doi :10.3892/ijo.25.3.759 . PMID 15138608 . ^ "Entrez Gene: JMJD2B jumonji domain containing 2B" .
Further reading
Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones" . DNA Res . 9 (3): 99–106. doi :10.1093/dnares/9.3.99 PMID 12168954 . Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19" . Nature . 428 (6982): 529–35. Bibcode :2004Natur.428..529G . doi :10.1038/nature02399 PMID 15057824 . Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5. Bibcode :2004PNAS..10112130B . doi :10.1073/pnas.0404720101 PMC 514446 PMID 15302935 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Gray SG, Iglesias AH, Lizcano F, et al. (2005). "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein" . J. Biol. Chem . 280 (31): 28507–18. doi :10.1074/jbc.M413687200 PMID 15927959 . Whetstine JR, Nottke A, Lan F, et al. (2006). "Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases" . Cell . 125 (3): 467–81. doi :10.1016/j.cell.2006.03.028 PMID 16603238 . S2CID 14461740 . Katoh Y, Katoh M (2007). "Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells" . Int. J. Mol. Med . 20 (2): 269–73. doi :10.3892/ijmm.20.2.269 PMID 17611647 . Deng P, Yuan Q, Cheng Y, et al. (2021). "Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging" . Cell Stem Cell . 28 (6): 1057–1073.e7. doi :10.1016/j.stem.2021.01.010 . PMC 8178178 PMID 33571444 .
Activity Regulation Classification Kinetics Types
