Endometrial stromal sarcoma (high-grade)

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Endometrial stromal sarcoma (high-grade)
SpecialtyOncology, gynecology
SymptomsAbnormal uterine bleeding, pelvic pain, mass of the uterus[1]
Usual onsetMid-40s[1]
FrequencyVery rare, only few cases reported worldwide[1]

High-grade endometrial stromal sarcoma (HGESS) is a type of cancer in the uterus.[2] It typically occurs in females in their 40s, and presents with abnormal uterine bleeding, pelvic pain, and mass of the uterus.[1]

It is a subtype of endometrial stromal tumor belonging to the mesenchymal tumors of the main body of the uterus.[1] It is distinct to and more aggressive than low-grade endometrial stromal sarcoma.[2]

The cause is not known.[1]

It is very rare, with only a few cases reported worldwide.[1] Although it may occur in females aged 14 to 71-years, the average age at presentation is in the mid-40s.[1] mass of the uterus[1]

See also


  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 WHO Classification of Tumours Editorial Board, ed. (2020). "6. Tumours of the uterine corpus: high-grade endometrial stromal sarcoma". Female genital tumours: WHO Classification of Tumours. Vol. 4 (5th ed.). Lyon (France): International Agency for Research on Cancer. pp. 289–291. ISBN 978-92-832-4504-9. Archived from the original on 2022-06-17. Retrieved 2022-07-30.
  2. 2.0 2.1 Howitt, Brooke E.; Nucci, Marissa R. (2019). "1. Uterine mesenchymal lesions". In Zheng, Wenxin; Fadare, Oluwole; Quick, Charles Matthew; Shen, Danhua; Guo, Donghui (eds.). Gynecologic and Obstetric Pathology. Vol. 2. Springer: Springer. pp. 8–10. ISBN 978-981-13-3018-6. Archived from the original on 2022-08-01. Retrieved 2022-07-30.

External links