|Other names: Deciduosis, decidualized endometriosis|
|Risk factors||Pregnancy, progestin use, trophoblastic disease, hormone producing ovarian lesions outside the ovary|
|Differential diagnosis||Luteinized sex cord stromal tumor, cancer spread from skin or lung.|
Ectopic decidua is the presence of decidual cells outside the uterus, typically in pregnancy. Generally there are no symptoms, and it is usually detected when investigating another problem. There may be a tummy ache if the appendix is involved.
It may be associated with trophoblastic disease, ovarian lesions outside the ovary that produce hormones, or the use of progestin. In pregnancy, sites of involvement include the appendix, inner cervix, uterus, fallopian tubes, bowel, bladder and omentum. Under the microscope, it may appear as a single nodule or a cluster of small nodules just under the peritoneal surface. If the lesion is large enough to be seen by direct visualisation, it may be mistaken for a cancer. It tends to resolve without significant complications after delivery of the baby. Other conditions that may appear similar include luteinized sex cord stromal tumor, and cancer spread from skin or lung.
It is most commonly seen during pregnancy; microscopically in all pregnancies and macroscopically in up to 10% of pregnancies. This condition was first described in 1971 by Walker and the name 'ectopic decidua' was coined by Tausig.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 WHO Classification of Tumours Editorial Board, ed. (2020). "3. Tumours of the peritoneum: Ectopic decidua". Female genital tumours: WHO Classification of Tumours. Vol. 4 (5th ed.). Lyon (France): International Agency for Research on Cancer. p. 206. ISBN 978-92-832-4504-9. Archived from the original on 2022-06-17. Retrieved 2022-07-30.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Suster, David; Liu, Martina Z.; Lin, Douglas I. (2019). "3. Benign diseases of the ovary". In Zheng, Wenxin; Fadare, Oluwole; Quick, Charles Matthew; Shen, Danhua; Guo, Donghui (eds.). Gynecologic and Obstetric Pathology. Vol. 2. Springer: Springer. pp. 89–90. ISBN 978-981-13-3018-6. Archived from the original on 2022-08-01. Retrieved 2022-07-30.
- ↑ Gilks, C. Blake (2019). "7. Peritoneum: Benign Mullein lesions". In Nucci, Marisa R.; Oliva, Esther (eds.). Diagnostic Pathology: Gynecological (2nd ed.). Philadelphia: Elsevier Health Sciences. p. 267. ISBN 978-0-323-54815-1. Archived from the original on 2022-08-01. Retrieved 2022-07-30.
- ↑ Bolat, Filiz (2012). "Pregnancy related peritoneal ectopic decidua: Morphological and clinical evaluation". Turkish Journal of Pathology. 28 (1): 56–60. doi:10.5146/tjpath.2012.01098. PMID 22207433.
- ↑ Ober, William (1957). "Ectopic ovarian decidua without pregnancy". American Journal of Pathology. 33 (2): 199–217. PMC 1934629. PMID 13402883.