Diabetic foot infection

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Diabetic foot infection
Gas gangrene due to diabetes
SymptomsPus from a wound, redness, swelling, pain, warmth[1]
ComplicationsInfection of the bone, tissue death, sepsis, amputation[2]
CausesDiabetic foot ulcer[2]
Diagnostic methodBased on symptoms[1]
Differential diagnosisPhlegmasia cerulea dolens, ischemic limb[2]
PreventionAppropriate shoes[2]
TreatmentWound care, antibiotics, hyperbaric oxygen therapy[2]

Diabetic foot infection is any infection of the foot in a diabetic.[2] Symptoms may include pus from a wound, redness, swelling, pain, or warmth.[1] Foot ulcers; however, may occur without being infected.[1] Complications can include infection of the bone, tissue death, amputation, or sepsis.[2]

They most often form following a diabetic foot ulcer.[2][1] Bacteria that are commonly involved include staphylococcus, streptococci, pseudomonas, and gram-negative bacteria.[2] The underlying mechanism often involves poor blood flow and peripheral neuropathy.[2] Diagnosis is based on symptoms and maybe supported by deep tissue culture.[2][1]

Prevention includes wearing appropriate shoes.[2] Treatment involves proper wound care and antibiotics.[2] The duration of antibiotics is often two to four weeks.[2] Hyperbaric oxygen therapy may also help.[2] They are common and occur equally frequently in males and females.[2] Older people are more commonly affected.[2]



For minor soft tissue infections cephalexin, clindamycin, or dicloxacillin by mouth may be used.[3] This is done for 1 to 4 weeks.[3]

For severe disease ciprofloxacin with clindamycin or piperacillin/tazobactam may be used.[3] This is done for 6 to 12 weeks.[3]


  1. 1.0 1.1 1.2 1.3 1.4 1.5 Lipsky, Benjamin A.; Berendt, Anthony R.; Deery, H. Gunner; Embil, John M.; Joseph, Warren S.; Karchmer, Adolf W.; LeFrock, Jack L.; Lew, Daniel P.; Mader, Jon T.; Norden, Carl; Tan, James S. (1 October 2004). "Diagnosis and Treatment of Diabetic Foot Infections". Clinical Infectious Diseases. 39 (7): 885–910. doi:10.1086/424846.
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 Murphy-Lavoie, HM; Ramsey, A; Nguyen, M; Singh, S (January 2020). "Diabetic Foot Infections". PMID 28722943. {{cite journal}}: Cite journal requires |journal= (help)
  3. 3.0 3.1 3.2 3.3 Bader, MS (1 July 2008). "Diabetic foot infection". American family physician. 78 (1): 71–9. PMID 18649613.