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Combination of
Cefoperazoneβ-Lactam antibiotic
Sulbactamβ-Lactamase inhibitor
Clinical data
Trade namesSulperazon
Legal status
Legal status
  • US: Discontinued[1]
  • In general: ℞ (Prescription only)

Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections.[2] It contains cefoperazone, a β-lactam antibiotic, and sulbactam, a β-lactamase inhibitor, which helps prevent bacteria from breaking down cefoperazone.[3]


  1. ^ "Cefoperazone". DrugBank.
  2. ^ Greenberg RN, Reilly PM, Weinandt WJ, Bollinger M, Kennedy DJ (1987). "Cefoperazone-sulbactam combination in the treatment of urinary tract infections: efficacy, safety, and effects on coagulation". Clinical Therapeutics. 10 (1): 52–6. PMID 3329965.
  3. ^ Singh GS (January 2004). "Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam". Mini Reviews in Medicinal Chemistry. 4 (1): 93–109. doi:10.2174/1389557043487547. PMID 14754446.