Xenotropic and polytropic retrovirus receptor 1

XPR1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5IJH
Identifiers
Aliases	XPR1, SYG1, X3, IBGC6, xenotropic and polytropic retrovirus receptor 1, SLC53A1
External IDs	OMIM: 605237 MGI: 97932 HomoloGene: 134226 GeneCards: XPR1
Gene location (Human) Chr. Chromosome 1 (human) Band 1q25.3 Start 180,632,022 bp End 180,890,279 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 G3|1 66.49 cM Start 155,151,447 bp End 155,293,161 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence secondary oocyte endothelial cell pancreatic epithelial cell islet of Langerhans Brodmann area 23 right ventricle endometrium middle temporal gyrus bronchial epithelial cell Top expressed in median eminence ventromedial nucleus arcuate nucleus habenula ascending aorta dorsomedial hypothalamic nucleus extensor digitorum longus muscle mammillary body triceps brachii muscle paraventricular nucleus of hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity transmembrane signaling receptor activity phosphate ion transmembrane transporter activity inositol hexakisphosphate binding virus receptor activity efflux transmembrane transporter activity signaling receptor activity Cellular component integral component of membrane membrane intrinsic component of plasma membrane plasma membrane cytoplasm Golgi apparatus Biological process viral entry into host cell G protein-coupled receptor signaling pathway response to virus cellular phosphate ion homeostasis phosphate ion transmembrane transport phosphate ion transport cellular response to phosphate starvation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9213 19775 Ensembl ENSG00000143324 ENSMUSG00000026469 UniProt Q9UBH6 Q9Z0U0 RefSeq (mRNA) NM_004736 NM_001135669 NM_001328662 NM_011273 RefSeq (protein) NP_001129141 NP_001315591 NP_004727 NP_035403 Location (UCSC) Chr 1: 180.63 – 180.89 Mb Chr 1: 155.15 – 155.29 Mb PubMed search
Wikidata
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Xenotropic and polytropic retrovirus receptor 1 is a protein that in humans is encoded by the XPR1 gene.

Further reading

• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Bhosle S, Suppiah S, Molinaro R, Liang Y, Arnold R, Diehl W, Makarova N, Blackwell J, Petros J, Liotta D, Hunter E, Ly H (2010). "Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells". J. Virol. 84 (13): 6288–96. doi:10.1128/JVI.00274-10. PMC 2903252. PMID 20410264.