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First section: The typos "drieded" and "mind-actering"—need to be changed "dried" and "mind-altering".
Change the abbreviation THC to "tetrahydrocannabinol (THC)".
At the end of first section add the sentence, Other active compounds include cannabidiol (CBD).
Fourth section: The word "subs" needs to be changed to "substances".
Bottom of image: the wording "Source CDC" and the URL needs to be removed.
Change all the green color in this image to match the green color in the next image below. There are of total of six icons that contain green color. This includes the green color in the smoke. Leave the pipe color as is.
The period (.) at the end of the title needs to be removed and make sure the title is centered after the period is removed. The title may need to be moved a hair to the right once the period is removed.
The period (.) after the sections names, Mental Health, Child Development, and Other Risks need to be removed.
Bottom of image: the wording "Source CDC" and the URL needs to be removed.
The spacing at the top and bottom may need to be adjusted after the CDC information is removed.
The period (.) at the end of the title needs to be removed and make sure the title is centered after the period is removed.
The period (.) after the sections name Poisoning need to be removed.
Update EVALI section: Vaping products containing THC and vitamin E acetate have been linked to a severe lung injury known as e-cigarette, or vaping, product use-associated lung injury (EVALI). Vaping products containing nicotine have also been linked to EVALI in a limited number of cases.
Bottom of image: the wording "Source CDC" and the URL needs to be removed.
The spacing at the top and bottom may need to be adjusted after the CDC information is removed.
Discussion

These files are only for MDWiki for now. They should not be transferred to other wikis. Send me an email of the file and I will upload new versions to each file name here.

Work area

Add one smaller, cyan-colored particle (same style as the other virus particles) slightly to the right side next to the existing ones in the top section by the woman's exhaled aerosol.

Change the entire background to pure white (#FFFFFF).

In the third text block, replace the final sentence so it reads exactly: "E-cigarette aerosol is considered hazardous to humans."

A woman with light brown, shoulder-length hair is shown inhaling from an e-cigarette. She wears a teal long-sleeved shirt and holds a black and navy blue e-cigarette in her right hand. A light blue cloud of aerosol is exhaled from her mouth. Floating near the aerosol cloud are three virus-like icons in different shades of blue, symbolizing harmful particles or contaminants.

In the bottom right corner, there are three larger virus-like icons in varying shades of blue, reinforcing the theme of airborne health risks.

File

E-Cigarette Health Risks & Uncertainties

  • Grana, Rachel; Benowitz, Neal; Glantz, Stanton A. (13 May 2014). "E-Cigarettes: A Scientific Review". Circulation. 129 (19): 1972–1986. doi:10.1161/circulationaha.114.007667. PMC 4018182. PMID 24821826.

See "The chronic effects of e-cigarettes remain unclear due to variability in study populations and a lack of consensus on what constitutes long-term exposure—ranging from as soon as 1 month to several years. Some experts believe the real long-term effects of e-cigarettes may only become apparent after decades."[1]

E-CIGARETTE HEALTH RISKS & UNCERTAINTIES

NICOTINE EXPOSURE Still addictive and harmful, especially for youth and pregnant women.[1]

AEROSOL CONTENTS May contain toxicants like formaldehyde, acetaldehyde, and heavy metals.[2]

SECOND-HAND EXPOSURE Not harmless—potential risks to bystanders.[3]

LONG-TERM EFFECTS Largely unknown due to limited data.[4]

File

New infographic: User:QuackGuru/Sand C.

Create a new infographic based on the following content: Some non-users have reported adverse effects from the second-hand aerosol. Studies have provided evidence about the health risks of e-cigarette passive exposure, which are, in some respects, comparable to those associated with passive tobacco exposure. Exhaled aerosol consists of nicotine and some other particles, primarily consisting of propylene glycol, glycerin, flavors, and aroma transporters. Bystanders are exposed to these particles from exhaled e-cigarette aerosol. The exhaled aerosol may involuntarily expose bystanders to toxicants that are in the range as some cigarettes This is due to the fact that some vaping devices generate toxicants in the range as some cigarettes do. Second-hand e-cigarette aerosol may be dangerous to children.

File

New infographic: User:QuackGuru/Sand 32.

Health Risks Associated with E-Cigarette Aerosol

Create a new infographic with a white background titled HEALTH RISKS ASSOCIATED WITH E-CIGARETTE AEROSOL based on the following content:

E-cigarette aerosol contains a variety of organic and inorganic toxicants and carcinogens. --> E-cigarette aerosol contains nicotine, organic and inorganic toxicants, and known carcinogens.

Exhaled e-cigarette aerosol releases these toxicants into the air, which potentially exposes non-users in residential and workplace environments. --> Exhaled e-cigarette aerosol emits these toxicants into the air, which potentially exposes non-users in residential and workplace environments.

There is limited data on the long-term effects of direct and second-hand e-cigarette aerosol exposure. E-cigarette aerosol is considered hazardous to humans. Include graphics such as a visual depiction of aerosol.

=={{int:filedesc}}==
{{Information
|description={{en|1=The content of the infographic draws on information from four sources about the health effects of e-cigarettes. It included four key health risks: nicotine exposure, aerosol contents, second-hand exposure, and long-term effects.}}
|date=2025-10-10
|source=The content of the infographic is based on information from four sources about the health effects of e-cigarettes. It included four key health risks: [https://pubmed.ncbi.nlm.nih.gov/36868366/ nicotine exposure], [https://pubmed.ncbi.nlm.nih.gov/40278584/ aerosol contents], [https://pubmed.ncbi.nlm.nih.gov/41007552/ second-hand exposure], and [https://pubmed.ncbi.nlm.nih.gov/39135931/ long-term effects].
*{{cite journal|last1=Castro|first1=Emily M.|last2=Lotfipour|first2=Shahrdad|last3=Leslie|first3=Frances M.|title=Nicotine on the developing brain|journal=Pharmacological Research|date=April 2023|volume=190|pages=106716|doi=10.1016/j.phrs.2023.106716|pmc=10392865|pmid=36868366}}
*{{cite journal|last1=Toledo|first1=Eduard Ferney Valenzuela|last2=Simões|first2=Ivana Ferreira|last3=Farias|first3=Marcel Tavares de|last4=Minho|first4=Lucas Almir Cavalcante|last5=Conceição|first5=Jaquelide de Lima|last6=Santos|first6=Walter Nei Lopes dos|last7=Mesquita|first7=Paulo Roberto Ribeiro de|last8=Júnior|first8=Aníbal de Freitas Santos|title=A Comprehensive Review of the Harmful Compounds in Electronic Cigarettes|journal=Toxics|date=31 March 2025|volume=13|issue=4|pages=268|doi=10.3390/toxics13040268|pmc=12031152|pmid=40278584}}
*{{cite journal|last1=Patanavanich|first1=Roengrudee|last2=Thatasawakul|first2=Chawaphat|last3=Youngcharoen|first3=Kamolnut|last4=Soponvashira|first4=Veerapattra|last5=Pichetsin|first5=Panpetch|title=Health Effects from Secondhand Exposure to E-Cigarettes: A Systematic Review of Peer-Reviewed Articles from 2004–2024|journal=International Journal of Environmental Research and Public Health|date=10 September 2025|volume=22|issue=9|pages=1408|doi=10.3390/ijerph22091408|pmc=12469341|pmid=41007552}}
*{{cite journal|last1=Izquierdo-Condoy|first1=Juan S.|last2=Naranjo-Lara|first2=Patricio|last3=Morales-Lapo|first3=Estefanía|last4=Hidalgo|first4=Marlon R.|last5=Tello-De-la-Torre|first5=Andrea|last6=Vásconez-Gonzáles|first6=Eduardo|last7=Salazar-Santoliva|first7=Camila|last8=Loaiza-Guevara|first8=Valentina|last9=Rincón Hernández|first9=Wendy|last10=Becerra|first10=Diego Alexander|last11=González|first11=María Belén Delgado|last12=López-Cortés|first12=Andrés|last13=Ortiz-Prado|first13=Esteban|title=Direct health implications of e-cigarette use: a systematic scoping review with evidence assessment|journal=Frontiers in Public Health|date=29 July 2024|volume=12|doi=10.3389/fpubh.2024.1427752|pmc=11317248|pmid=39135931}}
|author=[[User:QuackGuru|QuackGuru]]
|permission=
|other versions=
}}

=={{int:license-header}}==
{{self}}
{{cc-by-4.0}}

[[Category:Vaping-related graphics]]

Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation PMID: 34474637 DOI: 10.1080/01480545.2021.1972680

=={{int:filedesc}}==
{{Information
|description={{en|1=The content of the infographic draws on information from a 2022 reivew about the health risks associated with e-cigarette aerosol.}}
|date=2025-10-10
|source=The content of the infographic is based on information from a 2022 review found here: https://pubmed.ncbi.nlm.nih.gov/34474637/.
*{{cite journal|last1=Prasad|first1=Kedar N.|last2=Bondy|first2=Stephen C.|title=Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation|journal=Drug and Chemical Toxicology|date=2 November 2022|volume=45|issue=6|pages=2561–2567|doi=10.1080/01480545.2021.1972680|pmid=34474637}}
|author=[[User:QuackGuru|QuackGuru]]
|permission=
|other versions=
}}

=={{int:license-header}}==
{{self}}
{{cc-by-4.0}}

[[Category:Vaping-related graphics]]

Create a new infographic with a white background based on the following content: The aerosol contains varying amounts of organic and inorganic toxicants as well as carcinogens, which might serve as the source of such deleterious events. E-cigarette vaping releases these toxicants into the air leading to inhalation by nonsmokers in residential or workplace areas. Unlike regular tobacco smoke, the long-term consequences of direct and secondhand exposure to e-cigarette aerosol have not been extensively studied but based on available data, e-cigarette aerosol should be considered harmful to human health.

[5]

Create a new infographic titled E-CIGARETTE AEROSOL HEALTH RISKS based on the following source about what is found in the e-cigarette aerosol along with the harms: https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html

Changes are for all three infographics.

The content of the infographic highlights the health effects of e-cigarettes. It included six key health risks: nicotine addiction, underage brain development, lung damage, cardiovascular injury, EVALI, and nicotine poisoning.

=={{int:filedesc}}==
{{Information
|description={{en|1=The content of the infographic draws on information from three sources about the health effects of e-cigarettes. It included six key health risks: nicotine addiction, underage brain development, lung damage, cardiovascular injury, EVALI, and nicotine poisoning.}}
|date=2025-10-10
|source=The content of the infographic was copied from the CDC website with minor changes to layout, wording, and design for clarity—except for the section titled "Cardiovascular Injury" and for the section titled "EVALI." The original CDC source can be found here: https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html. The part regarding cardiovascular injury, "Nicotine can raise blood pressure and put stress on the heart," is sourced to a 2023 review found here: https://pubmed.ncbi.nlm.nih.gov/37458106/. The part regarding EVALI, "Vaping products containing THC and vitamin E acetate have been linked to a severe lung injury known as [[:en:vaping-associated pulmonary injury|e-cigarette, or vaping, product use-associated lung injury]] (EVALI). Vaping products containing nicotine have also been linked to EVALI in a limited number of cases," is sourced to a 2022 review found here: https://www.tandfonline.com/doi/full/10.1080/10408444.2022.2082918.
*{{cite web|url=https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html|title=Health Effects of Vaping|publisher=Centers for Disease Control and Prevention|date=31 January 2025}}
*{{cite journal|last1=Rose|first1=Jason J.|last2=Krishnan-Sarin|first2=Suchitra|last3=Exil|first3=Vernat J.|last4=Hamburg|first4=Naomi M.|last5=Fetterman|first5=Jessica L.|last6=Ichinose|first6=Fumito|last7=Perez-Pinzon|first7=Miguel A.|last8=Rezk-Hanna|first8=Mary|last9=Williamson|first9=Eric|title=Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products: A Scientific Statement From the American Heart Association|journal=Circulation|date=22 August 2023|volume=148|issue=8|pages=703–728|doi=10.1161/CIR.0000000000001160|pmid=37458106}}
*{{cite journal|last1=Marrocco|first1=Antonella|last2=Singh|first2=Dilpreet|last3=Christiani|first3=David C.|last4=Demokritou|first4=Philip|title=E-cigarette vaping associated acute lung injury (EVALI): state of science and future research needs|journal=Critical Reviews in Toxicology|date=16 March 2022|volume=52|issue=3|pages=188–220|doi=10.1080/10408444.2022.2082918|pmc=9716650|pmid=35822508}}
|author=[[User:QuackGuru|QuackGuru]]
|permission=
|other versions=
}}

=={{int:license-header}}==
{{self}}
{{cc-by-4.0}}

[[Category:Vaping-related graphics]]
Discussion

[6]

The content of the infographic is about the carcinogenicity of nicotine and its modulation of signaling pathways in cancer progression.

The content of the infographic is based on the following review: https://link.springer.com/article/10.1007/s10311-023-01668-1.

  • Rao, Zihan; Xu, Yuqin; He, Zihan; Wang, Juan; Ji, Huanhong; Zhang, Zhongwei; Zhou, Jianming; Zhou, Tong; Wang, Huai (November 2023). "Carcinogenicity of nicotine and signal pathways in cancer progression: a review". Environmental Chemistry Letters. 22 (1): 239–272. doi:10.1007/s10311-023-01668-1.

The second section has only two particles. I want it changed to three.

Place a tiny cyan colored particle in the second section underneath the particle on the left on its right edge side and align it so that it is slightly below the second particle on the right side.

https://link.springer.com/article/10.1007/s10311-023-01668-1

Generate an infographic:

Title name:

Carcinogenicity of Nicotine and Its Modulation of Signaling Pathways in Cancer Progression

Title Layout:

Carcinogenicity of Nicotine and Its Modulation of Signaling Pathways in Cancer Progression. Line 1: CARCINOGENICITY OF NICOTINE AND; Line 2: ITS MODULATION OF SIGNALING; Line 3: OF SIGNALING PATHWAYS IN CANCER PROGRESSION. Fit the entire title name in three lines and centered.

Alignment for title:

Centered.

Text color:

100% Black

Text:

A range of cancers has reportedly been linked to nicotine exposure. In addition to lung carcinoma, nicotine exposure has reportedly been associated with the development of cervical, colon, gastric, pancreatic, breast, liver, bladder, and head and neck cancers, including those affecting the nasopharynx, tongue, and oral cavity.

Emerging evidence, based on animal xenograft models and cell culture studies, indicates that nicotine's carcinogenic effects are driven by a variety of signaling mechanisms:

Signaling Pathways Nicotine can activate both receptor-independent and receptor-dependent pathways. Key receptors involved include nicotinic acetylcholine receptors, β-adrenergic receptors, epidermal growth factor receptors, and transforming growth factor β receptors.

Genotoxic Effects Nicotine may lead to chromosomal alterations, DNA damage, and the formation of micronuclei.

Oxidative Stress By increasing the production of reactive oxygen species, nicotine promotes oxidative stress, which can initiate or accelerate tumor development.

Collectively, these findings seem to indicate that nicotine acts as a potent cancer-causing agent that influences tumor cell proliferation, invasion, and migration through multiple biochemical pathways related to chemical carcinogenicity.

File

A person experiencing a tremor, caused by cessation of cannabis.

An illustration of a person experiencing a headache caused by cannabis consumption.

An illustration of a person experiencing symptoms of nausea caused by cannabis consumption.

An illustration of a person feeling nauseous caused by cannabis consumption.

An illustration of a person showing signs of nausea caused by cannabis consumption.

File

https://www.flickr.com/photos/nysdoh/48682896723

https://www.flickr.com/photos/nysdoh/48683410542

https://www.flickr.com/photos/nysdoh/48683410247

https://www.flickr.com/photos/nysdoh/albums/72157710703391248/

File

File:A montage of e-cigarette users performing vape tricks.gif

https://ezgif.com/maker

  1. Castro, Emily M.; Lotfipour, Shahrdad; Leslie, Frances M. (April 2023). "Nicotine on the developing brain". Pharmacological Research. 190: 106716. doi:10.1016/j.phrs.2023.106716. PMC 10392865. PMID 36868366.
  2. Toledo, Eduard Ferney Valenzuela; Simões, Ivana Ferreira; Farias, Marcel Tavares de; Minho, Lucas Almir Cavalcante; Conceição, Jaquelide de Lima; Santos, Walter Nei Lopes dos; Mesquita, Paulo Roberto Ribeiro de; Júnior, Aníbal de Freitas Santos (31 March 2025). "A Comprehensive Review of the Harmful Compounds in Electronic Cigarettes". Toxics. 13 (4): 268. doi:10.3390/toxics13040268. PMC 12031152. PMID 40278584.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  3. Patanavanich, Roengrudee; Thatasawakul, Chawaphat; Youngcharoen, Kamolnut; Soponvashira, Veerapattra; Pichetsin, Panpetch (10 September 2025). "Health Effects from Secondhand Exposure to E-Cigarettes: A Systematic Review of Peer-Reviewed Articles from 2004–2024". International Journal of Environmental Research and Public Health. 22 (9): 1408. doi:10.3390/ijerph22091408. PMC 12469341. PMID 41007552.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  4. Izquierdo-Condoy, Juan S.; Naranjo-Lara, Patricio; Morales-Lapo, Estefanía; Hidalgo, Marlon R.; Tello-De-la-Torre, Andrea; Vásconez-Gonzáles, Eduardo; Salazar-Santoliva, Camila; Loaiza-Guevara, Valentina; Rincón Hernández, Wendy; Becerra, Diego Alexander; González, María Belén Delgado; López-Cortés, Andrés; Ortiz-Prado, Esteban (29 July 2024). "Direct health implications of e-cigarette use: a systematic scoping review with evidence assessment". Frontiers in Public Health. 12. doi:10.3389/fpubh.2024.1427752. PMC 11317248. PMID 39135931.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  5. Prasad, Kedar N.; Bondy, Stephen C. (2 November 2022). "Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation". Drug and Chemical Toxicology. 45 (6): 2561–2567. doi:10.1080/01480545.2021.1972680. PMID 34474637.
  6. Rao, Zihan; Xu, Yuqin; He, Zihan; Wang, Juan; Ji, Huanhong; Zhang, Zhongwei; Zhou, Jianming; Zhou, Tong; Wang, Huai (November 2023). "Carcinogenicity of nicotine and signal pathways in cancer progression: a review". Environmental Chemistry Letters. 22 (1): 239–272. doi:10.1007/s10311-023-01668-1.