Classification
Classification of protein kinases can be done either by chemical (enzymatic) activity or structure. Chemical activity classifies protein kinases into the following categories:
| Category
|
EC number
|
| Serine/threonine protein kinase
|
2.7.11
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| Tyrosine protein kinase
|
2.7.10
|
| Dual-specificity kinase
|
2.7.12
|
| Histidine kinase
|
2.7.13
|
With respect to amino-acid sequence and thus structure the following families have been proposed:
| Family
|
Description
|
| CMGC
|
Cyclin-dependent kinases (CDKs), Mitogen-activated protein kinases (MAP kinases), Glycogen synthase kinases (GSK) and CDK-like kinases
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