USP42

USP42
Identifiers
Aliases	USP42, ubiquitin specific peptidase 42
External IDs	MGI: 1924050 HomoloGene: 35425 GeneCards: USP42
Gene location (Human) Chr. Chromosome 7 (human) Band 7p22.1 Start 6,104,949 bp End 6,161,564 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5 G2|5 82.5 cM Start 143,696,080 bp End 143,718,035 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm pancreatic epithelial cell pancreatic ductal cell Brodmann area 23 tibialis anterior muscle nipple postcentral gyrus entorhinal cortex testicle visceral pleura Top expressed in cumulus cell vas deferens utricle seminiferous tubule abdominal wall maxillary prominence foot medial ganglionic eminence superior cervical ganglion ureter More reference expression data BioGPS n/a
Gene ontology Molecular function cysteine-type peptidase activity protein binding peptidase activity hydrolase activity thiol-dependent deubiquitinase cysteine-type endopeptidase activity Cellular component nucleoplasm Biological process ubiquitin-dependent protein catabolic process spermatogenesis proteolysis cell differentiation protein deubiquitination regulation of apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84132 76800 Ensembl ENSG00000106346 ENSMUSG00000051306 UniProt Q9H9J4 B2RQC2 RefSeq (mRNA) NM_032172 NM_001365764 NM_001389650 NM_029749 RefSeq (protein) NP_115548 NP_001352693 NP_084025 Location (UCSC) Chr 7: 6.1 – 6.16 Mb Chr 5: 143.7 – 143.72 Mb PubMed search
Wikidata
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Ubiquitin carboxyl-terminal hydrolase 42 is an enzyme that in humans is encoded by the USP42 gene.

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.