Thionein

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Thionein is a cysteine-rich coenzyme associated with metallothioneins.[1] Thionein and metallothionein act as a redox pair, and much of the antioxidant functions of attributed to metallothionein are actually due to thionein.[1] The binding of heavy metal ions to both thionein and metallothionein is due to their high cysteine content.[2]

References

  1. ^ a b Wolfgang m (2003). "Cellular zinc and redox states converge in the metallothionein/thionein pair". Journal of Nutrition. 133 (5 Suppl 1): 1460S–142SS. doi:10.1093/jn/133.5.1460S. PMID 12730443.
  2. ^ Palacios O, Atrian S, Capdevila, M (2011). "Zn- and Cu-thioneins: a functional classification for metallothioneins?". Journal of Biological Inorganic Chemistry. 16 (7): 991–1009. doi:10.1007/s00775-011-0827-2. PMID 21823038. S2CID 26786966.


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