Tarlatamab

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Tarlatamab
Monoclonal antibody
Type?
Clinical data
Other namesAMG757; AMG-757
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
UNII

Tarlatamab is a bispecific T cell engager that binds DLL3 and CD3 which has shown promise for previously treated small cell lung cancer.[1]

References

  1. ^ Ahn, Myung-Ju; Cho, Byoung Chul; Felip, Enriqueta; Korantzis, Ippokratis; Ohashi, Kadoaki; Majem, Margarita; Juan-Vidal, Oscar; Handzhiev, Sabin; Izumi, Hiroki; Lee, Jong-Seok; Dziadziuszko, Rafal; Wolf, Jürgen; Blackhall, Fiona; Reck, Martin; Bustamante Alvarez, Jean (2023-11-30). "Tarlatamab for Patients with Previously Treated Small-Cell Lung Cancer". New England Journal of Medicine. 389 (22): 2063–2075. doi:10.1056/NEJMoa2307980. ISSN 0028-4793.