Talk:Ulinastatin

History of use

It has been used in JAPAN and CHINA for many years.It be effective in treatment of acute pancreatitis and acute circulatory failure. It will be used widely.There are two company, MOCHIDA and TECHPOOL. —Preceding unsigned comment added by Eva913 (talk • contribs) 02:17, 9 October 2009 (UTC)

What is the substance here?

The article prose talks about a ~25 kDa glycoprotein, but many of the drugbox fields instead refer to a spirodioxane–furan small molecule (File:3-(2-Furyl)-2,4-dioxaspiro(5.5)undec-8-ene.png). The linked wikidata:Q7879029 likewise has SMILES/InChI/etc for the small molecule but ontology of a glycoprotein. And the MeSH record from Wikidata says it's 68 kDa. SciFinder says Ulinastatin is CASNo 80449-31-6 and the small molecule is 80499-32-7 (separate records) whereas Pubchem lists both registry numbers in its Ulinastatin record and draws the small-molecule structure for it. Sounds like SciFinder is more reasonably correct, and PubChem and Wiki are in a feedback loop with an unknown starting point? DMacks (talk) 15:12, 28 April 2021 (UTC)

Checking SciFinder, the protein is 80449-32-7 whereas the small molecule is 80499-32-7. So the cross-contaminated database entries probably began as a simple typo in someone's manual keying. I cleaned up Wikidata, and now things here look self-consistent. DMacks (talk) 05:11, 29 April 2021 (UTC)