Talk:Gacyclidine

From WikiProjectMed
Jump to navigation Jump to search

The diagram of the gacyclidine molecule should be edited to depict the racemate, as the name "gacyclidine" does not specify a single enantiomer. To quote a paper on the subject "Gacyclidine [cis(pipGme)]-1-[1-(2-thienyl)-2-methylcyclohexylpiperidine] (Fig. 2) is a PCP derivative bearing a 2-thienyl group as an aromatic moiety and a methyl group at carbon 2. The methyl group introduces a chiral center and, therefore, gacyclidine is a racemate of two enantiomers, (+)GK11 [(+)-(1R-2S)-1-[1-(2-thienyl)-2-methylcyclohex- ylpiperidine] and (–)GK11 [(–)-(1S-2R)-1-[1-(2-thienyl)-2-methylcyclohexylpiperidine]...Since it is a racemate, the binding characteristics of the two enantiomers have also been determined in parallel (41)."

so replace the hatches and wedges with straight lines or adders. Valerophenone (talk) 02:17, 9 February 2011 (UTC)[reply]