TMX1

TMX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1X5E
Identifiers
Aliases	TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1
External IDs	OMIM: 610527 MGI: 1919986 HomoloGene: 12482 GeneCards: TMX1
Gene location (Human) Chr. Chromosome 14 (human) Band 14q22.1 Start 51,240,162 bp End 51,257,655 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 C2 Start 70,499,869 bp End 70,514,814 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibia germinal epithelium trabecular bone oral cavity jejunal mucosa superficial temporal artery secondary oocyte retinal pigment epithelium monocyte periodontal fiber Top expressed in retinal pigment epithelium cumulus cell ciliary body Paneth cell fossa condyle aortic valve supraoptic nucleus ascending aorta iris More reference expression data BioGPS n/a
Gene ontology Molecular function disulfide oxidoreductase activity protein disulfide isomerase activity Cellular component integral component of membrane membrane endoplasmic reticulum membrane endoplasmic reticulum Biological process protein folding response to endoplasmic reticulum stress cell redox homeostasis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81542 72736 Ensembl ENSG00000139921 ENSMUSG00000021072 UniProt Q9H3N1 Q8VBT0 RefSeq (mRNA) NM_030755 NM_028339 RefSeq (protein) NP_110382 NP_082615 Location (UCSC) Chr 14: 51.24 – 51.26 Mb Chr 12: 70.5 – 70.51 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi:10.1038/nature01348. PMID 12508121.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.