STMN3

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STMN3
Identifiers
AliasesSTMN3, SCLIP, stathmin 3
External IDsOMIM: 608362; MGI: 1277137; HomoloGene: 7528; GeneCards: STMN3; OMA:STMN3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001276310
NM_015894

NM_009133

RefSeq (protein)

NP_001263239
NP_056978

NP_033159

Location (UCSC)n/aChr 2: 180.95 – 180.96 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Stathmin-3 is a protein that in humans is encoded by the STMN3 gene.[4][5][6]

Function

The protein encoded by this gene belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.[6]

Interactions

STMN3 has been shown to interact with TRPC5.[7]

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027581Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Ozon S, Byk T, Sobel A (June 1998). "SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system". Journal of Neurochemistry. 70 (6): 2386–96. doi:10.1046/j.1471-4159.1998.70062386.x. PMID 9603203. S2CID 1252160.
  5. ^ Bai C, Connolly B, Metzker ML, Hilliard CA, Liu X, Sandig V, Soderman A, Galloway SM, Liu Q, Austin CP, Caskey CT (February 2000). "Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster". Proceedings of the National Academy of Sciences of the United States of America. 97 (3): 1230–5. Bibcode:2000PNAS...97.1230B. doi:10.1073/pnas.97.3.1230. PMC 15578. PMID 10655513.
  6. ^ a b "Entrez Gene: STMN3 stathmin-like 3".
  7. ^ Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). "TRPC5 is a regulator of hippocampal neurite length and growth cone morphology". Nature Neuroscience. 6 (8): 837–45. doi:10.1038/nn1092. PMID 12858178. S2CID 7523946.

Further reading