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Perfluorohexyloctane

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Perfluorohexyloctane
Names
Trade namesMiebo
Other namesNOV03; 1-(perfluorohexyl)octane
  • 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane
Clinical data
Main usesDry eye disease[1]
Side effectsBlurry vision[1]
Routes of
use
Eye drop[1]
Typical dose1 drop QID[1]
Legal
License data
Legal status
Chemical and physical data
FormulaC14H17F13
Molar mass432.269 g·mol−1
3D model (JSmol)
  • CCCCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
  • InChI=1S/C14H17F13/c1-2-3-4-5-6-7-8-9(15,16)10(17,18)11(19,20)12(21,22)13(23,24)14(25,26)27/h2-8H2,1H3
  • Key:WRYIIOKOQSICTB-UHFFFAOYSA-N

Perfluorohexyloctane, sold under the brand name Miebo is a medication used for the treatment of dry eye disease.[1] It is used as an eye drop.[1]

Side effects may include blurry vision.[1] It is a semifluorinated alkane and believed to work by preventing evaporation of tears.[1]

Perfluorohexyloctane was approved for medical use in the United States in 2023.[1] In the United States it costs about 780 USD for a 3 ml bottle as of 2023.[2]

Medical uses

Perfluorohexyloctane is indicated for the treatment of the signs and symptoms of dry eye disease.[1]

Dosage

It is used as one drop four times per day.[1]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 "Miebo- perfluorohexyloctane solution". DailyMed. 18 May 2023. Archived from the original on 14 August 2023. Retrieved 8 June 2023. Archived 14 August 2023 at the Wayback Machine
  2. "Miebo". GoodRx. Archived from the original on 21 March 2024. Retrieved 14 August 2023. Archived 21 March 2024 at the Wayback Machine

External links

Identifiers: