PRR4

PRR4
Identifiers
Aliases	PRR4, LPRP, PROL4, proline rich 4 (lacrimal), proline rich 4
External IDs	OMIM: 605359 HomoloGene: 48512 GeneCards: PRR4
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.2 Start 10,845,849 bp End 10,849,475 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in salivary gland minor salivary glands duodenum skin of abdomen substantia nigra hippocampus proper amygdala hypothalamus Brodmann area 9 pituitary gland n/a More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 11272 n/a Ensembl ENSG00000111215 ENSG00000282269 ENSG00000263247 n/a UniProt Q16378 n/a RefSeq (mRNA) NM_007244 NM_001098538 n/a RefSeq (protein) NP_001092008 NP_009175 n/a Location (UCSC) Chr 12: 10.85 – 10.85 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Proline-rich protein 4 is a protein that in humans is encoded by the PRR4 gene.

Lacrimal proline rich protein is a member of the proline-rich protein family which lacks a conserved repetitive domain. It may have a role in protective functions in the eye.

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Fung KY, Morris C, Sathe S, et al. (2005). "Characterization of the in vivo forms of lacrimal-specific proline-rich proteins in human tear fluid". Proteomics. 4 (12): 3953–9. doi:10.1002/pmic.200300849. PMID 15526346. S2CID 42700978.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.