Nodavirus endopeptidase

From WikiProjectMed
Jump to navigation Jump to search
Nodavirus endopeptidase
Identifiers
EC no.3.4.23.44
CAS no.852954-38-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Nodavirus endopeptidase (EC 3.4.23.44, Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-Ala- or -Asn-Phe-

The enzyme is coded by several nodaviruses that are insect pathogens.

References

  1. ^ Zlotnick A, Reddy VS, Dasgupta R, Schneemann A, Ray WJ, Rueckert RR, Johnson JE (May 1994). "Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue". The Journal of Biological Chemistry. 269 (18): 13680–4. PMID 8175803.
  2. ^ Johnson JE, Schneemann A (1998). "Nodavirus endopeptidase". In Barrett AJ, Rawlings ND, Woessner JF (eds.). Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 964–967.

External links