N-methylalanine dehydrogenase
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| N-methylalanine dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.4.1.17 | ||||||||
| CAS no. | 56379-51-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a N-methylalanine dehydrogenase (EC 1.4.1.17) is an enzyme that catalyzes the chemical reaction
- N-methyl-L-alanine + H2O + NADP+ pyruvate + methylamine + NADPH + H+
The 3 substrates of this enzyme are N-methyl-L-alanine, H2O, and NADP+, whereas its 4 products are pyruvate, methylamine, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating).
References
- Lin MC, Wagner C (1975). "Purification and characterization of N-methylalanine dehydrogenase". J. Biol. Chem. 250 (10): 3746–51. PMID 236301.
