Mucor fragilis

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Mucor fragilis
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Fungi
Division: Mucoromycota
Order: Mucorales
Family: Mucoraceae
Genus: Mucor
Species:
M. fragilis
Binomial name
Mucor fragilis
Bainier, 1884

Mucor fragilis is an endophytic fungus that causes the mold that can be found on grapes, pole beans, loquat, and on the roots of medicinal plants like Radix pseudostellariae.[1][2][3][4] It belongs to the order Mucorales and phylum Mucoromycota. The observed symptoms showed the presence of fluffy and soft fungal mycelium with white to dark brown discoloration that deteriorated the beans and grapes quality.[2]

Taxonomy

Mucor fragilis was described by Bainier in 1884.

Description

Mucor fragilis is described to have colonies that vary in color from white and reverse white to light gray.[5] Mucor fragilis reproduces asexually and the sporangiophores are found as two types: simple and sympodially branched.[6] Sporangiophores are mostly sympodially branched and grow to a width of around 6–12 µm and have a variable length.[6] These sporangiophores have globose to subglobose, multispored, light yellow sporangia on them that measure around 24.5–49.5 by 22.5–48 µm.[6] The columellae of Mucor fragilis can be globose to ellipsoid, pyriform, or some conical and can measure around 17.5–30 by 16–29.5 µm. The columellae collar is evident.[6]

Habitat and distribution

This species is isolated from soil, insects, fruits, honeycomb, limestone, and plasticized polyvinyl chloride. It is distributed worldwide in places like Australia, Brazil, Bulgaria, China, Czech Republic, Germany, Greece, India, Iran, Kenya, Korea, Lithuania, Mexico, Pakistan, Poland, Portugal, Spain, Switzerland, and the United States. It is known in 3 of the 26 states in Brazil.[5]

Ecology

Mucor fragilis is causing rot on lots of plant species in China and Pakistan. It has been found on grapes in five different locations of fruit markets after harvest in Pakistan and has causes a decline in the market value of grapes.[1] Thyme oil has been found to potentially increase the shelf-life of these grapes.[1] Also in Pakistan, Mucor fragilis has been causing rot in seychelles pole beans.[2] This is the first time this fungus has been seen on pole beans and is causing urgency to control this fungus so it does not spread.[2] In China, Mucor fragilis has been found on one of China's highly prized medicinal plants (Radix pseudostellariae).[4] This is also the first report of Mucor fragilis causing rot on this plant and could result in loss of production of this medical plant.[4] Mucor fragilis was found on deceased adult reproductive female brown widow spiders (Latrodectus geometricus) in North Central Florida.[7] Spiders first showed signs of reduced foraging behavior and then started to die, this confirms that Mucor fragilis is pathogenic to these spiders.[7] Mucor fragilis releases spores that can infect species like these spiders in multiple ways such as in their food or wound exposure. A study done on enzymes from Mucor fragilis grown on bovine blood provides a discussion on how this fungus be helpful to study structures on glycoconjugates containing certain glycoproteins.[8] The view is that blood has nutritional value and is wasted when producing meat and the goal was to find a way to reuse this biomass and with a little more research, enzymes of Mucor fragilis may be the answer to the problem.[8]

Bioactive metabolites

Mucor fragilis can produce simultaneously two bioactive metabolites, podophyllotoxin and kaempferol, as its host plant.[9] This is very significant for this fungus as podophyllotoxin is in great demand due to its use as an anticancer and antivirus drug precursor.[9] As the podophyllum plant is endangered, having Mucor fragilis produce podophyllotoxin can help increase the production of podophyllotoxin and also help the endangered podophyllum plant from going extinct.[9] Mucor fragilis is an effective endophytic fungal elicitor as it has shown enhancement features of some primary and secondary metabolites in Salvia miltiorrhiza hairy roots.[10]

References

  1. ^ a b c Ghuffar, S (2018). "Cultural, morphological, pathogenic and molecular characterization of Mucor fragilis causing bunch rot of grapes in Pakistan and its bio management through plant essential oil". International Journal of Biosciences.
  2. ^ a b c d Khan, Iqra Haider; Javaid, Arshad (2022-05-01). "Mucor fragilis causing rot of seychelles pole bean in Pakistan". Australasian Plant Pathology. 51 (3): 359–362. Bibcode:2022AuPP...51..359K. doi:10.1007/s13313-022-00859-8. ISSN 1448-6032. S2CID 247427268.
  3. ^ Naeem, and Muhammd; Abbas, Muhammad Fahim; Naz, Farah; Batool, Sana; Qamar, Misbah Iqbal (2020-01-16). "First evidence of Mucor rot infecting loquat (Eriobotrya japonica L.) in Pakistan". Mycopath. 16 (2). ISSN 1729-5521.
  4. ^ a b c Wu, Hongmiao; Wu, Jiachun; Li, Feng; Zheng, Ling; Fan, Jingkai; Lin, Wenxiong (2021-04-01). "First Report of Mucor spp. Causing Root Rot of Radix pseudostellariae in Guizhou Province of China". Plant Disease. 105 (4): 1200. doi:10.1094/PDIS-07-20-1634-PDN. ISSN 0191-2917. PMID 33074068. S2CID 224779439.
  5. ^ a b "Mucor fragilis". iucn.ekoo.se. Retrieved 2023-05-05.
  6. ^ a b c d Nguyen, T (December 2016). "Characterization of Two New Records of Mucoralean Species Isolated from Gut of Soldier Fly Larva in Korea". Mycobiology. 44 (4): 310–313. doi:10.5941/MYCO.2016.44.4.310. PMC 5287164. PMID 28154489.
  7. ^ a b Bibbs, C. S. (September 2013). "Susceptibility of Latrodectus geometricus (Araneae: Theridiidae) to a Mucor Strain Discovered in North Central Florida, USA". Florida Entomologist. 96 (3): 1052–1061. doi:10.1653/024.096.0344. S2CID 26573695.
  8. ^ a b Yamamoto, Kenji; Tsuji, Yasunobu; Matsushita, Sawako; Kumagai, Hidehiko; Tochikura, Tatsurokuro (May 1986). "Purification and Properties of β- N -Acetylhexosaminidase from Mucor fragilis Grown in Bovine Blood". Applied and Environmental Microbiology. 51 (5): 1019–1023. Bibcode:1986ApEnM..51.1019Y. doi:10.1128/aem.51.5.1019-1023.1986. ISSN 0099-2240. PMC 239004. PMID 16347047.
  9. ^ a b c Huang, Jian-Xin; Zhang, Jun; Zhang, Xiao-Rui; Zhang, Kun; Zhang, Xiao; He, Xiao-Rui (2014-10-01). "Mucor fragilis as a novel source of the key pharmaceutical agents podophyllotoxin and kaempferol". Pharmaceutical Biology. 52 (10): 1237–1243. doi:10.3109/13880209.2014.885061. ISSN 1388-0209. PMID 24863281. S2CID 9662947.
  10. ^ Xu, Wenjuan; Jin, Xiaoyan; Yang, Miao; Xue, Song; Luo, Linglong; Cao, Xupeng; Zhang, Caijuan; Qiao, Sanyang; Zhang, Chi; Li, Junling; Wu, Jiahui; Lv, Liqiao; Zhao, Fangyuan; Wang, Nan; Tan, Shuting (2021-03-01). "Primary and secondary metabolites produced in Salvia miltiorrhiza hairy roots by an endophytic fungal elicitor from Mucor fragilis". Plant Physiology and Biochemistry. 160: 404–412. doi:10.1016/j.plaphy.2021.01.023. ISSN 0981-9428. PMID 33571807. S2CID 231900529.
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