Momilactone-A synthase
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| Momilactone-A synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.295 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Momilactone-A synthase (EC 1.1.1.295, momilactone A synthase, OsMAS) is an enzyme with systematic name 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide:NAD(P)+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P)+ momilactone A + NAD(P)H + H+
The rice phytoalexin momilactone A is a diterpenoid secondary metabolite that is involved in the defense mechanism of the plant. Momilactone A is produced in response to attack by a pathogen through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation.
References
- ^ Atawong A, Hasegawa M, Kodama O (March 2002). "Biosynthesis of rice phytoalexin: enzymatic conversion of 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide to momilactone A". Bioscience, Biotechnology, and Biochemistry. 66 (3): 566–70. doi:10.1271/bbb.66.566. PMID 12005050. S2CID 83339044.
- ^ Shimura K, Okada A, Okada K, Jikumaru Y, Ko KW, Toyomasu T, Sassa T, Hasegawa M, Kodama O, Shibuya N, Koga J, Nojiri H, Yamane H (November 2007). "Identification of a biosynthetic gene cluster in rice for momilactones". The Journal of Biological Chemistry. 282 (47): 34013–8. doi:10.1074/jbc.M703344200. PMID 17872948.
External links
- Momilactone-A+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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