MAGEA5

MAGEA5P
Identifiers
Aliases	MAGEA5P, CT1.5, MAGE5, MAGEA4, MAGE family member A5, MAGE family member A5, pseudogene, MAGEA5
External IDs	OMIM: 300340 HomoloGene: 130448 GeneCards: MAGEA5P
Gene ontology Molecular function molecular function Cellular component cellular component Biological process regulation of chromosome segregation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4104 n/a Ensembl ENSG00000242520 n/a UniProt P43359 n/a RefSeq (mRNA) NM_021049 n/a RefSeq (protein) NP_066387 n/a Location (UCSC) n/a n/a PubMed search n/a
Wikidata
View/Edit Human

Melanoma antigen family A, 5 is a protein in humans that is encoded by the MAGEA5 gene.

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011].