Protein-coding gene in the species Homo sapiens
KIF1-binding protein, also known as Kinesin binding protein(KBP), is a protein that in humans is encoded by the KIAA1279 gene .[5] [6] [7] [8]
Clinical significance Defects may be associated with Goldberg–Shprintzen syndrome (OMIM 609460).
Interactions KIAA1279 has been shown to interact with Retinal G protein coupled receptor [9] Dipeptidase 1 .[9]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000198954 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036955 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: KIAA1279 KIAA1279" .^ Brouwers N, Mallol Martinez N, Vernos I (2017-04-26). "Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment" . PLOS ONE . 12 (4): e0174819. Bibcode :2017PLoSO..1274819B . doi :10.1371/journal.pone.0174819 PMC 5405935 PMID 28445502 . ^ Vanneste D, Takagi M, Imamoto N, Vernos I (November 2009). "The role of Hklp2 in the stabilization and maintenance of spindle bipolarity" . Current Biology . 19 (20): 1712–7. Bibcode :2009CBio...19.1712V . doi :10.1016/j.cub.2009.09.019 PMID 19818619 . ^ Sebastian J, Rathinasamy K (July 2019). "Benserazide Perturbs Kif15-kinesin Binding Protein Interaction with Prolonged Metaphase and Defects in Chromosomal Congression: A Study Based on in silico Modeling and Cell Culture". Molecular Informatics . 39 (3): minf.201900035. doi :10.1002/minf.201900035 . PMID 31347789 . S2CID 198911009 . ^ a b Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Further reading
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Molecular Systems Biology . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 . Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801–14. doi :10.1016/j.cell.2006.03.032 PMID 16713569 . S2CID 13709685 . Wozniak MJ, Melzer M, Dorner C, Haring HU, Lammers R (October 2005). "The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein" . BMC Cell Biology . 6 : 35. doi :10.1186/1471-2121-6-35 PMC 1266353 PMID 16225668 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Brooks AS, Bertoli-Avella AM, Burzynski GM, Breedveld GJ, Osinga J, Boven LG, et al. (July 2005). "Homozygous nonsense mutations in KIAA1279 are associated with malformations of the central and enteric nervous systems" . American Journal of Human Genetics . 77 (1): 120–6. doi :10.1086/431244 . PMC 1226183 PMID 15883926 . Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (October 1999). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Research . 6 (5): 337–45. doi :10.1093/dnares/6.5.337 PMID 10574462 .
External links
