Isonotholaenic acid

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Isonotholaenic acid
Chemical structure of isonotholaenic acid
Names
Preferred IUPAC name
4-Hydroxy-2-methoxy-6-[2-(4-methoxyphenyl)ethyl]benzoic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C17H18O5/c1-21-14-7-4-11(5-8-14)3-6-12-9-13(18)10-15(22-2)16(12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20)
    Key: GAWSNXBLUNVZCK-UHFFFAOYSA-N
  • InChI=1/C17H18O5/c1-21-14-7-4-11(5-8-14)3-6-12-9-13(18)10-15(22-2)16(12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20)
    Key: GAWSNXBLUNVZCK-UHFFFAOYAW
  • c2cc(OC)ccc2CCc1cc(O)cc(OC)c1C(O)=O
Properties
C17H18O5
Molar mass 302.326 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Isonotholaenic acid is a dihydrostilbenoid found in the Andean fern Argyrochosma nivea (formerly Notholaena nivea).[1] This compound shows an anti-chagasic activity.[2]

References

  1. ^ del Olmo, Esther; Armas, Marlon Garcia; Ybarra, Ma Inèss; Lopez, José Luis; Oporto, Patricia; Giménez, Alberto; Deharo, Eric; San Feliciano, Arturo (2003). "The Imidazo[2,1-a]isoindole System. A New Skeletal Basis for Antiplasmodial Compounds". Bioorganic & Medicinal Chemistry Letters. 13 (16): 2769–2772. doi:10.1016/S0960-894X(03)00509-2. PMID 12873511.
  2. ^ del Olmo, Esther; Armas, Marlon Garcia; López-Pérez, JL; Ruiz, G; Vargas, F; Giménez, Alberto; Deharo, Eric; San Feliciano, Arturo (2001). "Anti-Trypanosoma activity of some natural stilbenoids and synthetic related heterocyclic compounds". Bioorganic & Medicinal Chemistry Letters. 11 (20): 2755–2757. doi:10.1016/s0960-894x(01)00562-5. PMID 11591517.
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