Iraj Lalezari

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Iraj Lalezari
Born4 July 1930
Hamadan, Qajar Iran
Died31 July 2019(2019-07-31) (aged 89)
Boulder, Colorado, US
Resting placeGreen Mountain Cemetery, Boulder, CO, US
Education
  • Organic chemistry
  • Pharmacology
Alma mater
Children2
AwardsLavoisier Medal
Scientific career
Fields
  • Organic chemistry
  • Pharmacology
Institutions

Iraj Lalezari (1930–2019) was an Iranian academic of Jewish origin. His study fields were organic chemistry and pharmacology. He left Iran in 1979 following the regime change in the country and settled in the US where he continued his academic studies.

Early life and education

Lalezari was born in Hamadan on 4 July 1930.[1][2] He was the eldest of four siblings.[3] He received a degree in pharmacology from the University of Tehran.[1] He obtained his PhD in pharmacology from his alma mater in 1951.[4] He also received a PhD in organic chemistry from the University of Sorbonne in 1953.[1][4] He carried out his post-doctorate studies in organic chemistry at the same institution in 1954.[4]

Career and activities

Following his graduation, Lalezari joined the University of Tehran where he served as the chair of the chemistry department (1970–1978) and the dean of the pharmacology faculty (1973–1979).[3] In 1964 he was promoted to a professorship in organic chemistry.[4] He was named as the chair of the Iranian Pharmaceutical Association in 1975 which he held until 1979.[4] In 1976 he was made a member of the Iranian Royal Academy of Sciences.[4] In 1977 he established the Institute at Medicinal Plants at the University of Tehran which he headed until 1979.[4]

He had to leave Iran due to the establishment of an Islamic government in February 1979 and continued his academic studies in New York City[3] where he worked at the Montefiore Medical Center and Albert Einstein College of Medicine.[5] He served as the director of medicinal chemistry in the latter.[6]

Lalezari was part of the Iranian Jewish delegation led by Moussa Kermanian who met with President Jimmy Carter in 1980.[3] The goal of the meeting was to facilitate the migration of Iranian Jews to the US.[3]

He was a member of the American Jewish Federation and the Maccabee Foundation based in New York.[7] In 2006 Lalezari retired from academic life.[3]

Patents and work

Lalezari had numerous patents which he obtained between February 1977 and May 2015, including treatments for Alzheimer's disease using gene therapy methodologies.[8][9] Some of these patents were taken jointly by him and his brother Parviz.[10][11]

Iraj Lalezari discovered the hemoglobin A1C test which has been used in many countries to diagnose diabetes.[3] He also invented some compounds of fluoride and selenium.[3]

Later years, personal life and death

Lalezari was married and had two sons.[1] Following his retirement he settled in Colorado and continued his studies at his home laboratory.[3] In 2010 he joined Cell Viable, a company that develops and produces skincare products.[6] He died in Boulder, Colorado, on 31 July 2019.[2][3] He was buried at the Green Mountain Cemetery in Boulder on 2 August.[12]

Awards

Lalezari was the recipient of the Lavoisier Medal which was granted to him in 1954 by the French Chemical Society.[3][4] He was also awarded by the Shah Mohammad Reza Pahlavi and Empress Farah Pahlavi for his outstanding studies.[3][4]

References

  1. ^ a b c d "Iraj Lalezari". 7dorim. 7 November 2021. Retrieved 28 January 2023.
  2. ^ a b "Dr. Iraj Lalezari". echovita. Retrieved 28 January 2023.
  3. ^ a b c d e f g h i j k l Karmel Melamed. "Iranian Jews mourn passing of scientific giant Dr. Iraj Lalezari". Jewish News Syndicate. Retrieved 28 January 2023.
  4. ^ a b c d e f g h i "Biographical Sketch. Iraj Lalezari". Graduate Society Foundation. Retrieved 28 January 2023.
  5. ^ Iraj Lalezari (May–June 1985). "One-step synthesis of 3-amino-2,4-imidazolinediones (3-aminohydantoins) from α-amino acids". Journal of Heterocyclic Chemistry. 22 (3): 741–743. doi:10.1002/jhet.5570220325.
  6. ^ a b "Our Story". Cell Viable. 24 January 2019. Retrieved 28 January 2023.
  7. ^ "About The Maccabee Foundation". Maccabee Foundation. Retrieved 28 January 2023.
  8. ^ "Patents by Inventor Iraj Lalezari". Justia Patents. Retrieved 28 January 2023.
  9. ^ "Patent summary. Novel inhibitors of formation of advanced glycation endproducts (ages)". United States National Library of Medicine. Retrieved 28 January 2023.
  10. ^ "Method of synthesis and novel compounds for pharmaceutical uses (WO1989012622A1)". Google patents. Retrieved 28 January 2023.
  11. ^ Official Gazette of the United States Patent and Trademark Office: Patents. Washington,DC: U.S. Department of Commerce, Patent and Trademark Office. 2000. p. 1-PA581.
  12. ^ "Dr. Iraj Lalezari. 1930 - 2019". Legacy. Retrieved 28 January 2023.
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