Hexose oxidase

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hexose oxidase
Identifiers
EC no.1.1.3.5
CAS no.9028-75-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a hexose oxidase (EC 1.1.3.5) is an enzyme that catalyzes the chemical reaction

D-glucose + O2 D-glucono-1,5-lactone + H2O2

Thus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are D-glucono-1,5-lactone and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is D-hexose:oxygen 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, copper.

References

  • BEAN RC, HASSID WZ (1956). "Carbohydrate oxidase from A red alga, Iridophycus flaccidum". J. Biol. Chem. 218 (1): 425–36. PMID 13278350.
  • BEAN RC, PORTER GG, STEINBERG BM (1961). "Carbohydrate metabolism of citrus fruits. II. Oxidation of sugars by an aerodehydrogenase from young orange fruits". J. Biol. Chem. 236: 1235–40. PMID 13688220.
  • Sullivan JD, Ikawa M (1973). "Purification and characterization of hexose oxidase from the red alga Chondrus crispus". Biochim. Biophys. Acta. 309 (1): 11–22. doi:10.1016/0005-2744(73)90312-4. PMID 4708670.