GCM2

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GCM2
Identifiers
AliasesGCM2, GCMB, hGCMb, glial cells missing homolog 2, HRPT4, glial cells missing transcription factor 2, FIH2
External IDsOMIM: 603716 MGI: 1861438 HomoloGene: 3490 GeneCards: GCM2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004752

NM_008104

RefSeq (protein)

NP_004743

NP_032130

Location (UCSC)Chr 6: 10.87 – 10.88 MbChr 13: 41.25 – 41.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chorion-specific transcription factor GCMb is a protein that in humans is encoded by the GCM2 gene.[5][6]

The Drosophila 'glial cells missing' (gcm) gene is thought to act as a binary switch between neuronal and glial cell determination. The gcm protein and mammalian gcm homologs contain a conserved N-terminal gcm motif that has DNA-binding activity. See GCM1 (MIM 603715).[supplied by OMIM][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124827 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021362 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kanemura Y, Hiraga S, Arita N, Ohnishi T, Izumoto S, Mori K, Matsumura H, Yamasaki M, Fushiki S, Yoshimine T (Feb 1999). "Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene". FEBS Lett. 442 (2–3): 151–6. doi:10.1016/S0014-5793(98)01650-0. PMID 9928992. S2CID 2469563.
  6. ^ a b "Entrez Gene: GCM2 glial cells missing homolog 2 (Drosophila)".

Further reading