Fox 21 may refer to:
Television stations in the United States:
- WHNS Greenville, South Carolina
- WFXR Roanoke, Virginia (as "Fox 21/27")
- KXRM-TV Colorado Springs, Colorado
- KQDS-TV Duluth, Minnesota
- WBOC-DT2, Salisbury, Maryland
Other uses:
Topics referred to by the same term