File:Types of e-cigarette-induced DNA damage.png
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 10:58, 28 March 2024 | | 3,095 × 2,168 (992 KB) | commons>Ameisenigel | {{Information |Description=Types of e-cig-induced DNA damage. The dominant pathway of nicotine metabolism in humans is the formation of cotinine, the first step of which is catalyzed by cytochrome P450 (CYP P450). Nicotine can be metabolized to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N’-nitrosonornicotine (NNN). Both of these compounds, as well as acrolein (y-OH-Acr-dGUO), can lead to DNA adduct formation. E-cig aerosol-induced reactive oxygen species (ROS) can also induce DN... |
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