Familial progressive hyperpigmentation

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Familial progressive hyperpigmentation
Other names: Melanosis universalis hereditaria[1]
Dark mottled pigmentation on hands

Familial progressive hyperpigmentation is characterized by patches of hyperpigmentation, present at birth, which increase in size and number with age. This is a genetic disease, however the gene that accounts for this spotty darkening of the skin has yet to be discovered. Although rare, the congenital disease is most prevalent among populations originating from China.[2]: 858 

This condition in inherited in an autosomal dominant manner

See also


  1. RESERVED, INSERM US14-- ALL RIGHTS. "Orphanet: Familial progressive hyperpigmentation". www.orpha.net. Archived from the original on 9 October 2015. Retrieved 20 April 2019.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

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