FEM-1689
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Formula | C21H22F3NO |
Molar mass | 361.408 g·mol−1 |
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FEM-1689 is a drug which acts as a potent and selective sigma-2 receptor ligand with a binding affinity of 11 nM, and was developed for the treatment of neuropathic pain.[1]
References
- ^ Yousuf MS, Sahn JJ, Yang H, David ET, Shiers S, Mancilla Moreno M, et al. (December 2023). "Highly specific σ2R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response". Proceedings of the National Academy of Sciences of the United States of America. 120 (52): e2306090120. Bibcode:2023PNAS..12006090Y. doi:10.1073/pnas.2306090120. PMC 10756276. PMID 38117854.
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