EML4

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EML4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEML4, C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120, echinoderm microtubule associated protein like 4, EMAP like 4
External IDsOMIM: 607442 MGI: 1926048 HomoloGene: 56841 GeneCards: EML4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145076
NM_019063

RefSeq (protein)

NP_001138548
NP_061936

Location (UCSC)Chr 2: 42.17 – 42.33 MbChr 17: 83.66 – 83.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Echinoderm microtubule-associated protein-like 4 is a protein that in humans is encoded by the EML4 gene.[5]

This protein is involved in cancers when spliced with the anaplastic lymphoma kinase.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143924 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032624 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: EML4 echinoderm microtubule associated protein like 4".
  6. ^ Choi YL, Takeuchi K, Soda M, Inamura K, Togashi Y, Hatano S, Enomoto M, Hamada T, Haruta H, Watanabe H, Kurashina K, Hatanaka H, Ueno T, Takada S, Yamashita Y, Sugiyama Y, Ishikawa Y, Mano H (July 2008). "Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer". Cancer Res. 68 (13): 4971–6. doi:10.1158/0008-5472.CAN-07-6158. PMID 18593892.

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: Q9HC35 (Human Echinoderm microtubule-associated protein-like 4 (EML4)) at the PDBe-KB.