EGOT, also known as EosinophilGranuleOntogeny (EGO)† Transcript (non-protein coding),[3] is a humangene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 (ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression.[3] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals.[4]
†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature.[5]
