Donovan's solution
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| Names | |
|---|---|
| IUPAC name
Iodomercury; triiodoarsane
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| Other names
Liquor hydriodatis arsenici et hydrargyri
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| RTECS number |
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| UN number | 1557 |
CompTox Dashboard (EPA)
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| Properties | |
| AsHgI4 | |
| Molar mass | 783.12948 |
| Appearance | Clear, colourless, or pale yellow. Darkens with age. |
| Boiling point | 403 °C (757 °F; 676 K) at 760 mmHg |
| Yes | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Toxic |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Donovan's solution is an inorganic compound prepared from arsenic triiodide and mercuric iodide.[1] Despite its name, it is a compound and not a solution.
Method
Donovan's solution can be prepared by mixing arsenic triiodide, mercuric iodide, and sodium bicarbonate in aqueous solution.[2][3]
Cooley's cyclopædia of practical receipts and ... information on the arts, manufactures, and trades gives a more complex method.[4]
Uses
The solution been used in veterinary medicine to treat chronic diseases of the skin[3] and as a folk remedy.[5] It was used during the 19th century to treat lepra vulgaris[6] and psoriasis[7][8] in humans, taken internally.
References
- ^ Budavari, Susan (1989). "3413. Donovan's Solution". The Merck Index (11th ed.). Merck & Co., Inc. p. 537. ISBN 091191028X. LCCN 89060001.
- ^ Navy Department. Bureau of Medicine and Surgery (1950). Pharmacy and Materia Medica: Military-medical Operations Courses. Bureau of Naval Personnel. p. 17.
- ^ a b Oxtoby, David W.; H.P. Gillis; Allan Campion (2012). Principles of modern chemistry (7th ed.). Belmont, Calif.: Brooks/Cole Cengage Learning. p. 513. ISBN 978-0840049315.
- ^ Arnold James Cooley (1880). "Solution". In Richard Vine Tuson (ed.). A cyclopædia of practical receipts and ... information on the arts, manufactures, and trades. Vol. II (6th ed.). p. 1525.
- ^ "Donovan's solution". Chemical Dictionary Online. Retrieved 29 November 2013.
- ^ Sir Erasmus Wilson (1847). "Treatment of Lepra". On Diseases of the Skin (2nd ed.). John Churchill. p. 271.
- ^ Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson, Low, Marston, Searle & Rivington. p. 254.
- ^ "Good Results of Donovan's Solution in Psoriasis". The Lancet. 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0.