Deacetylisoipecoside synthase
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| deacetylisoipecoside synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.3.3.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme deacetylisoipecoside synthase (EC 4.3.3.3) catalyzes the chemical reaction
- deacetylisoipecoside + H2O dopamine + secologanin
This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). It is also called deacetylisoipecoside dopamine-lyase. It participates in indole and ipecac alkaloid biosynthesis.
References
- De-Eknamkul W, Ounaroon A, Tanahashi T, Kutchan TM, Zenk MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry. 45 (3): 477–484. doi:10.1016/S0031-9422(96)00828-X.
