Comamonas testosteroni
| Comamonas testosteroni | |
|---|---|
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Scientific classification 
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| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Betaproteobacteria |
| Order: | Burkholderiales |
| Family: | Comamonadaceae |
| Genus: | Comamonas |
| Species: | C. testosteroni
|
| Binomial name | |
| Comamonas testosteroni (Marcus and Talalay 1956) Tamaoka et al. 1987
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| Synonyms | |
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Comamonas testosteroni is a Gram-negative environmental bacterium capable of utilizing testosterone as a carbon source, and degrading other sterols such as ergosterol and estrogens.[1] Strain I2gfp has been used in bioaugmentation trials, in attempts to treat the industrial byproduct 3-chloroaniline.[2] It was first classified as a human pathogen in 1987 according to the National Library of Medicine. A number of strains of Comamonas, including C. testosteroni, have been shown to consume terephthalic acid, one of the components of PET plastic, as a sole carbon source.[3]
Virulence
Though these organisms have low virulence, they can occasionally cause human diseases. They can be found in intravenous catheters, the respiratory tract, abdomen, urinary tract, and the central nervous system. Symptoms of infection may variously include vomiting, watery diarrhea, and meningitis.[4]
References
- ^ Liu, Na; Shi, Yue-e; Li, Jialu; Zhu, Meiling; Zhang, Tingdi (September 2021). "Identification and genome analysis of Comamonas testosteroni strain JLU460ET, a novel steroid-degrading bacterium". 3 Biotech. 11 (9): 404. doi:10.1007/s13205-021-02949-8. PMC 8353041. PMID 34458066.
- ^ Boon, Nico; Goris, Johan; De Vos, Paul; Verstraete, Willy; Top, Eva M. (July 2000). "Bioaugmentation of Activated Sludge by an Indigenous 3-Chloroaniline-Degrading Comamonas testosteroni Strain, I2 gfp". Applied and Environmental Microbiology. 66 (7): 2906–2913. Bibcode:2000ApEnM..66.2906B. doi:10.1128/AEM.66.7.2906-2913.2000. PMC 92090. PMID 10877785.
- ^ Schläfli, H R; Weiss, M A; Leisinger, T; Cook, A M (November 1994). "Terephthalate 1,2-dioxygenase system from Comamonas testosteroni T-2: purification and some properties of the oxygenase component". Journal of Bacteriology. 176 (21): 6644–6652. doi:10.1128/jb.176.21.6644-6652.1994. ISSN 0021-9193. PMC 197021. PMID 7961417.
- ^ Farooq, Shaika; Farooq, Rumana; Nahvi, Nahida (31 January 2017). "Comamonas testosteroni: Is It Still a Rare Human Pathogen". Case Reports in Gastroenterology. 11 (1): 42–47. doi:10.1159/000452197. PMC 5301100. PMID 28203137.
External links
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