Clofexamide

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Clofexamide
Clinical data
Routes of
administration		Oral, rectal, topical
ATC code
  • None
Legal status
Legal status
  • Discontinued
Identifiers
  • 2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.013.592 Edit this at Wikidata
Chemical and physical data
FormulaC14H21ClN2O2
Molar mass284.78 g·mol−1
3D model (JSmol)
  • CCN(CC)CCNC(=O)COC1=CC=C(C=C1)Cl
  • InChI=1S/C14H21ClN2O2/c1-3-17(4-2)10-9-16-14(18)11-19-13-7-5-12(15)6-8-13/h5-8H,3-4,9-11H2,1-2H3,(H,16,18)
  • Key:UORGKWWJEQDTGX-UHFFFAOYSA-N

Clofexamide (or amichlophene) is an antidepressant that was a component of the drug combination clofezone, the other being the nonsteroidal anti-inflammatory drug (NSAID) phenylbutazone. Clofezone was used to treat joint and muscular pain, but is not marketed any more.[1][2]

References

  1. ^ Berger A, Wachter H, eds. (1998). Hunnius Pharmazeutisches Wörterbuch (in German) (8 ed.). Walter de Gruyter Verlag. p. 343. ISBN 3-11-015793-4.
  2. ^ Reinicke C, Helbing M, Klingenfeld U, Lasaroff I, Wessel G (December 1984). "[Comparative studies on the bioavailability of various drug forms of phenylbutazone and clofezone (Perclusone)]". Die Pharmazie. 39 (12): 824–7. PMID 6241720.
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