Cephaeline
Jump to navigation
Jump to search
Names | |
---|---|
IUPAC name
7′,10,11-Trimethoxyemetan-6′-ol
| |
Systematic IUPAC name
(1R)-1-{[(2S,3R,11bS)-3-Ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl]methyl}-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | |
Other names
Cepheline; Desmethylemetine; Dihydropsychotrine
| |
Identifiers | |
3D model (JSmol)
|
|
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.902 |
KEGG | |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C28H38N2O4 | |
Molar mass | 466.622 g·mol−1 |
Appearance | White silky crystals |
Solubility in ethanol | Soluble[vague] |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
|
Emetic / poisonous |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine.
Poison treatment
Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3]
References
- ^ Lara, Alfonso; Valverde, Roberto; Gomez, Luis; Hidalgo, Nancy (July 1, 2003). "Micropropagacion de la planta medicinal psychotria acuminata". Agronomía Costarricense. Retrieved 26 December 2009.
- ^ "Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel". Chemical Business Newsbase. November 14, 2000. Retrieved 26 December 2009.
- ^ American Academy Of Pediatrics Committee On Injury, Violence (November 2003). "Policy statement: Poison treatment in the home". Pediatrics. 112 (5): 1182–1185. doi:10.1542/peds.112.5.1182. PMID 14595067.
Categories:
- Articles without InChI source
- ECHA InfoCard ID from Wikidata
- All Wikipedia articles needing clarification
- Wikipedia articles needing clarification from March 2015
- Articles containing unverified chemical infoboxes
- Articles with short description
- Short description matches Wikidata
- Isoquinoline alkaloids
- Phenols
- Norsalsolinol ethers
- Emetics
- Drugs with no legal status