Carotenoid isomerooxygenase

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Carotenoid isomerooxygenase
Identifiers
EC no.1.13.11.65
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Carotenoid isomerooxygenase (EC 1.13.11.65, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing).[1] This enzyme catalyses the following chemical reaction

zeaxanthin + O2 (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal .

References

  1. ^ Oberhauser V, Voolstra O, Bangert A, von Lintig J, Vogt K (December 2008). "NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide". Proceedings of the National Academy of Sciences of the United States of America. 105 (48): 19000–5. Bibcode:2008PNAS..10519000O. doi:10.1073/pnas.0807805105. PMC 2596218. PMID 19020100.

External links